EVALUATIVE STUDY OF OXIDATIVE STRESS MARKERS IN THE PATIENTS OF TUBERCULOSIS: A COMPARATIVE STUDY.
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Keywords
Tuberculosis, Oxidative stress marker, Super oxidase dismutase (SOD), C- reactive protein (CRP) and Nitric Oxide (NO)
Abstract
Background: An imbalance in oxidative stress status (OS) may be caused by pulmonary tuberculosis (TB), which is well recognized. In underdeveloped nations, socioeconomic and nutritional status are the primary determinants of tuberculosis (MTB) prevalence, which is the leading cause of mortality on a worldwide scale.
Aim: The purpose of this research was to examine oxidative stress indicators in individuals with pulmonary tuberculosis (PTB).
Methods: The present study was conducted on 50 patients of Tuberculosis and 50 normal healthy individuals. the study was carried out in biochemistry department of Santiniketan medical college Bolpur Birbhum West Bengal. Oxidative stress marker super oxidase dismutase, nitric oxide and serum C-reactive protein were analyzed for both groups. One way ANOVA statistical tool was applied to find out the statistical significance of the study.
Result: In our study we have found increased level of serum CRP and SOD in patients of tuberculosis, and nitric oxide was lower in TB patients as compared to normal subjects.
Conclusion: Our current research shows that oxidative stress is quite prevalent in tuberculosis
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Bijendra Singh Hindoliya
Assistant professor, Biochemistry Department of Santiniketan medical College Bolpur Birbhum West Bengal (731204)
Aniket Paul
Assistant professor, Biochemistry Department of Santiniketan medical College Bolpur Birbhum West Bengal (731204)
Junaid Musarrat Khan
Dr. Junaid Musarrat Khan: Assistant professor, Microbiology Department of Rohilkhand Medical college and Hospital, Bareilly, Uttar Pradesh, 243006
Bikramaditya Mukherjee
Assistant Professor, Department of Biochemistry, Manipal Tata Medical College, Manipal Academy of Higher Education, Manipal, India. 831017, Mobile /WhatsApp no: +91 94337 76315