CLINICAL, BIOCHEMICAL, RADIOLOGICAL AND ENDOSCOPIC PROFILE OF EXTRAHEPATIC BILIARY TRACT OBSTRUCTION IN TERTIARY CARE CENTRE OF NORTH INDIA
Main Article Content
Keywords
Biliary obstruction, jaundice, choledocholithiasis, stricture
Abstract
Background: Extrahepatic biliary obstruction has a variety of benign and malignant causes. choledocholithiasis among benign causes whereas carcinoma of gall blader and carcinoma of head of pancreas & ampullary carcinoma are common among malignant causes. Initial treatment of cases of extrahepatic biliary obstruction depends on cause of the biliary obstruction and the clinical status of patients.
Aims and objective: To study the clinical, biochemical, radiological and endoscopic profile in EHBO patients
Material and Methods: The present study was a prospective observational study conducted in 100 patients with extrahepatic biliary obstruction admitted in M. M. Institute of Medical Sciences & Research, Mullana. Written informed consent was taken. The diagnosis of EHBO was based on clinical history, clinical findings, radiological and biochemical investigation. Detailed history was taken and relevant investigation were done which included CBC, LFT, PT/INR, USG abdomen, MRCP &/or CT Abdomen. ERCP was also done as indicated.
Result: The mean age of study participants was 50.68 years. 63% of cases were seen in females whereas 37% were seen in males. 77% of subjects had benign causes whereas 23% had malignancy. CBD Stone was the most common cause seen in benign causes whereas GB carcinoma was the most common cause of malignancy.
Conclusion: The present study shows that benign cause are more common for extrahepatic biliary obstruction than the malignant ones. Moreover, benign causes occur in younger individuals than malignant causes which occur in higher age groups. ERCP serves as both diagnostic and therapeutic procedure in both benign and malignant cases and helps to alleviate the symptoms of EHBO.
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Dr Kapil Dev
Ex-Senior Resident, Department of Gastroenterology, MMIMSR, Mullana
Dr Vivek Ahuja
Associate Professor, Department of Gastroenterology MMIMSR, Mullana.
Dr Aakash Aggarwal
Assistant Professor, Department of Gastroenterology, MMIMSR, Mullana