STUDY OF PHYTOCHEMICALS AND ANTI -ULCER ACTIVITY OF BRASSICA OLERECEA
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Keywords
Peptic ulcer, Phytochemical, Brassica olerecea, Ulcer index, Herbal medicine, Pylorus ligation
Abstract
Brassica oleracea, commonly known as cruciferous vegetables, has been recognized for its rich phytochemical composition and potential health benefits. In this study, we conducted a comprehensive investigation into the phytochemical profile of Brassica oleracea extract and explored its anti-ulcer activity, particularly focusing on its efficacy in mitigating gastric ulcers. Phytochemical screening revealed the presence of various bioactive compounds, including alkaloids, carbohydrates, proteins and amino acids, saponins, phenols and tannins, and phytosterols/triterpenoids. Furthermore, we evaluated the anti-ulcer activity of Brassica oleracea extract using experimental models of gastric ulcers induced by pylorus ligation. Our findings demonstrated promising results, indicating a significant reduction in gastric secretion volume, total acidity, ulcer score, and ulcer index upon treatment with Brassica oleracea extract. These observations suggest the potential therapeutic benefits of Brassica oleracea in managing gastric ulcers. Overall, our study highlights the pharmacological potential of Brassica oleracea as a natural remedy for gastric ulcer management. Further research is warranted to elucidate the underlying mechanisms of its anti-ulcer activity and optimize dosage regimens for enhanced efficacy and safety. Brassica oleracea holds promise as a novel therapeutic agent derived from natural sources for the treatment of gastric ulcers, offering potential benefits for human health and well-being
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Neeraj Bansal
Adina institute of Pharmaceutical Science, Sagar (M.P.)
Arpit Shrivastava
Adina institute of Pharmaceutical Science, Sagar (M.P.)
Prateek Kumar Jain
Adina institute of Pharmaceutical Science, Sagar (M.P.)
Harshita Jain
Adina institute of Pharmaceutical Science, Sagar (M.P.)
Sunil Kumar Jain
Adina institute of Pharmaceutical Science, Sagar (M.P.)
Megha Shrivastava
Adina institute of Pharmaceutical Science, Sagar (M.P.)