CORRELATION BETWEEN CLINICAL AND HISTOLOGICAL CHARACTERISTICS OF BURNING MOUTH SYNDROME
Main Article Content
Keywords
burning mouth syndrome, histology, tongue, oral mucosa
Abstract
This study looked into the relationship between the histology and clinical characteristics of burning mouth syndrome (BMS). Individuals who experienced BMS symptoms for a minimum of six months underwent clinical and histological evaluations. Preliminary assessments included recording mean age, diabetes mellitus, menopausal status, length of non-irritable and irritative salivation or symptoms, and oral hygiene. Clinical trials were conducted on the following conditions: headache, pain, non-specific health issues, taste, thirst, dry mouth, and severe menopausal symptoms. Blood tests for HBS Ag, CBC and S. Iron, S. Ferritin, S. Folic acid as well as testing for female hormones including iron, folic acid, TSH, FT3, T4, and estrogen, were among the laboratory tests. The tongue is subjected to a prospective, blind histological examination, and mucosal samples are prepared for light microscopy. The Statistical Package of Social Science (SPSS) version 23 computer statistical program (SPSS Inc. Chicago, USA) was used to compile the data that had been gathered. The tongue and oral mucosa were examined for variations in their histological and clinical characteristics using the Chi Squire and Student's t-tests. P-values less than 0.05 are regarded as statistically significant. In summary, BMS is linked to xerostomia, altered taste on laboratory examination, physical and psychological stress, and histological characteristics that may indicate a source of neuropathy.
References
2.KC S, Shantaraj SL. Etiology, diagnosis and management of burning mouth syndrome: an update. Journal of Advanced Oral Research. 2012;3(3):7-12.
3.Coculescu EC, Ţovaru Ş, Coculescu BI. Epidemiological and etiological aspects of burning mouth syndrome. Journal of Medicine and Life. 2014;7(3):305.
4.Klasser GD, Grushka M, Su N. Burning mouth syndrome. Oral and Maxillofacial Surgery Clinics. 2016;28(3):381-96.
5.Mijajlović M, Zidverc-Trajković J, Stanimirović D, Janković L, Šternić N. Clinical and psychiatric manifestations of burning mouth syndrome. Aktuelnosti iz neurologije, psihijatrije i graničnih područja. 2011;19(3-4):37-43.
6.Gerlinger I. Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice. Ideggyogyaszati Szemle. 2012;65(9-10):295-301.
7.Maltsman‐Tseikhin A, Moricca P, Niv D. Burning mouth syndrome: will better understanding yield better management?. Pain practice. 2007;7(2):151-62.
8.Abetz LM, Savage NW. Burning mouth syndrome and psychological disorders. Australian dental journal. 2009;54(2):84-93.
9.Ching V, Grushka M, Darling M, Su N. Increased prevalence of geographic tongue in burning mouth complaints: a retrospective study. Oral surgery, oral medicine, oral pathology and oral radiology. 2012;114(4):444-8.
10.Moore PA, Guggenheimer J, Orchard T. Burning mouth syndrome and peripheral neuropathy in patients with type 1 diabetes mellitus. Journal of diabetes and its complications. 2007;21(6):397-402.
11.Coculescu EC, Radu A, Coculescu BI. Burning mouth syndrome: a review on diagnosis and treatment. Journal of Medicine and Life. 2014 Oct;7(4):512-515.
12.Maltsman‐Tseikhin A, Moricca P, Niv D. Burning mouth syndrome: will better understanding yield better management?. Pain practice. 2007;7(2):151-162.
13.Scala A, Checchi L, Montevecchi M, Marini I, Giamberardino MA. Update on burning mouth syndrome: overview and patient management. Critical Reviews in Oral Biology & Medicine. 2003;14(4):275-91.
14.Kapur N, Kamel IR, Herlich A. Oral and craniofacial pain: diagnosis, pathophysiology, and treatment. International anesthesiology clinics. 2003;41(3):115-150.
15.Gurvits GE, Tan A. Burning mouth syndrome. World journal of gastroenterology: WJG. 2013;19(5):665-672.
16.Svensson P, Bjerring P, Arendt-Nielsen L, Kaaber S. Sensory and pain thresholds to orofacial argon laser stimulation in patients with chronic burning mouth syndrome. The Clinical journal of pain. 1993;9(3):207-215.
17.Forssell H, Jääskeläinen S, Tenovuo O, Hinkka S. Sensory dysfunction in burning mouth syndrome. Pain. 2002;99(1-2):41-47.
18.Heckmann SM, Heckmann JG, HiIz MJ, Popp M, Marthol H, Neundörfer B, Hummel T. Oral mucosal blood flow in patients with burning mouth syndrome. Pain. 2001 ;90(3):281-286.
19.Lawson W, Blitzer A. Inflammatory and neoplastic lesions of the oral cavity. Clinics in Dermatology. 1987;5(2):43-58.
20.Gandhi B, Dhuvad J, Johnson A, Bhavsar D. Reactive lesions of oral cavity. Natl J Integr Res Med. 2016;7(4):154-57.
21.Long RG, Hlousek L, Doyle JL. Oral manifestations of systemic diseases. The Mount Sinai journal of medicine, New York. 1998;65(5-6):309-15.
22.Ito M, Kurita K, Ito T, Arao M. Pain threshold and pain recovery after experimental stimulation in patients with burning mouth syndrome. Psychiatry and clinical neurosciences. 2002;56(2):161-8.
23.Gao J, Chen L, Zhou J, Peng J. A case–control study on etiological factors involved in patients with burning mouth syndrome. Journal of oral pathology & medicine. 2009;38(1):24-8.
24.Kim MJ, Kho HS. Understanding of burning mouth syndrome based on psychological aspects. Chin J Dent Res. 2018;21(1):9-19.
25.Annino DJ, Goguen LA. Pain from the oral cavity. Otolaryngologic Clinics of North America. 2003;36(6):1127-35.
26.Valenzuela S, Lopez‐Jornet P. Effects of low‐level laser therapy on burning mouth syndrome. Journal of oral rehabilitation. 2017;44(2):125-32.
27.Dahiya P, Kamal R, Kumar M, Gupta R, Chaudhary K. Burning mouth syndrome and menopause. International Journal of Preventive Medicine. 2013;4(1):15-20
28.Bergdahl J, Anneroth G, Perris H. Personality characteristics of patients with resistant burning mouth syndrome. Acta Odontologica Scandinavica. 1995;53(1):7-11.
29.Bergdahl M, Bergdahl J. Burning mouth syndrome: prevalence and associated factors. Journal of Oral Pathology & Medicine. 1999;28(8):350-4.
30.Gao S, Wang Y, Wang Z. Assessment of trigeminal somatosensory evoked potentials in burning mouth syndrome. Chinese Journal of Dental Research. 2000;3:40-46.
31.Rabiei M, Leili EK, Alizadeh L ‘Burning Mouth Syndrome: A Comparative Cross-sectional Study’ Contemporary Clinical Dentistry. 2018; 9(Suppl 2): 256-260.
32.Ni Riordain R, O’Dwyer S, McCreary C. Burning mouth syndrome—a diagnostic dilemma. Irish Journal of Medical Science (1971-). 2019 Aug 1;188:731-734.
33.Penza P, Majorana A, Lombardi R, Camozzi F, Bonadeo S, Sapelli P, Lauria G. “Burning tongue” and “burning tip”: the diagnostic challenge of the burning mouth syndrome. The Clinical journal of pain. 2010 Jul 1;26(6):528-32.
34.Klein B, Thoppay JR, De Rossi SS, Ciarrocca K. Burning mouth syndrome. Dermatologic Clinics. 2020;38(4):477-83.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Mozammal Hossain
Professor, Department of Conservative Dentistry & Endodontics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.Lubna Khandker
Associate Professor, Dept of Dermatology and Venereology. Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Mst. Dil Afroz Bhuiyan
Assistant Professor, Department of Science of Dental Materials, Chattogram International Dental College, Chittagong, Bangladesh.
Sabequn Nahar-E-Farzana
Lecturer, Conservative Dentistry , Sir Salimullah Medical College, Dhaka, Bangladesh.
Rahela Yeasmin
Junior Consultant, Chittagong Medical College Hospital, Chittagong, Bangladesh.
Tanzir Hassan Siddique
Assistant Professor, Dental Public Health Department, Gonoshasthaya Samajvittik Medical College Dental Unit, Savar, Bangladesh.