STUDY OF ASSOCIATION BETWEEN SERUM FERRITIN LEVELS AT TERM PREGNANCY IN WOMEN WITH IRON DEFICIENCY ANAEMIA (IDA) AND NEW BORN SERUM FERRITIN LEVELS
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Keywords
Serum Ferritin Levels, Pregnancy, IDA, New-Born Serum Ferritin Levels.
Abstract
Background: In order to determine whether there is an association between the two, we compared the haemoglobin and serum ferritin levels of newborns delivered vaginally or by caesarean section to those of non-anaemic mothers and their newborns with iron deficiency anaemia.
Methods: The study involved recruiting 150 full-term mothers who were admitted through the OPD or labour room of Department of Obstetrics and Gynaecology, with age ranging from 18 to 40 years, who were in labour and had full-term new-borns without any prenatal or perinatal complications. The study was conducted at the Department of Obstetrics and Gynaecology, in a Tertiary care hospital of eastern India.
Results: During their pregnancy, 61% of patients did not take IFA (Iron Folic acid), compared to 28% of controls. The results of the analysis and computation of the p-value indicated that the data was statistically significant. The analysis revealed a strong link between the haemoglobin & serum ferritin levels of mothers and newborns. We applied the Spearman-Rho correlation test because the data was not normally distributed, and the results were significant. Because neonates delivered from Iron deficiency anaemia (IDA) women had considerably lower haemoglobin and ferritin concentrations than newborns delivered from non-anaemic (NA) mothers, maternal IDA has an impact on the iron reserve of newborns. To established relationship between the haemoglobin status of mothers and newborns in cases and controls, an independent t-test was used to
analyse the data, and statistical significance was observed.
Conclusion: Maternal IDA may have an impact on newborns' iron reserve. For foetal development to occur in utero and for storage of sufficient iron at birth to support growth in the early stages of infancy, there must be an ideal transfer of iron across the placenta. It appears that foetal iron requirements could be partially satisfied but not completely satisfied if maternal iron resources were exhausted. More research is needed to determine the association of the degree of lower cord serum Ferritin (SF) with the iron status and the developmental outcome of later part of infancy.
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Dr. Smruti Ranjan Jena
Senior Resident, Department of Obstetrics and Gynaecology, SCB Medical College, Cuttack, Odisha, India.
Dr. Saumya Nanda
Associate Professor, Department of Obstetrics and Gynaecology, Shri Jagannath Medical College, Puri, Odisha, India.
Dr. Bibhu Prasad Nayak
Associate Professor Department of Paediatrics, Dharanidhar Medical College and Hospital, Keonjhar, Odisha, India.
Dr Bipsa Singh
Associate Professor, Department of Paediatrics, Shri Jagannath Medical College, Puri, Odisha, India
Dr. Puspanjali Khuntia
Associate Professor, Department of Obstetrics and Gynaecology, Government Medical College and Hospital, Sundargarh, , Odisha, India