DELTAMETHRIN-INDUCED CHANGES IN GROWTH, HEMATOLOGICAL RESPONSES, AND OXIDATIVE STRESS LEVELS IN Gallus gallus domesticus
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Keywords
Deltamethrin, Gallus gallus domesticus, pyrethroid, toxicological impact hematological responses, oxidative stress biomarkers, sustainable pest management
Abstract
Deltamethrin, a type-II pyrethroid and synthetic-cyno pyrethroid, is extensively employed as an insecticide in agricultural and pest management practices. This study aims to investigate the toxicological impact of deltamethrin exposure on Gallus gallus domesticus, focusing on hematological, biochemical, histopathological, and growth parameters. Gallus gallus domesticus (chickens) were divided into four groups, including a control group and three experimental groups exposed to increasing doses of deltamethrin. Hematological parameters, biochemical markers, oxidative stress biomarkers, and histopathological changes in the liver were assessed. The study also examined the influence of deltamethrin on growth parameters, including weight and length. The study revealed significant adverse effects of deltamethrin exposure on various parameters in Gallus gallus domesticus, including hematological, biochemical, histopathological, and growth parameters. Dose-dependent reductions in hemoglobin, red blood cells, and hematocrit, coupled with increased oxidative stress biomarkers and liver enzyme levels, indicated potential toxicity. Histopathological examinations underscored substantial liver damage. Moreover, a dose-dependent impact on growth parameters highlighted significant weight and length reduction in exposed chickens. These findings emphasize the need for use of deltamethrin in poultry farming and the development of sustainable pest management practices to safeguard both poultry health and human consumers.
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Maida Bilal
Department of Zoology, The University of Lahore, Sargodha Campus, Sargodha-40100, Pakistan
Naila Amjad
Department of Zoology, The University of Lahore, Sargodha Campus, Sargodha-40100, Pakistan
Aasma Iqbal
Department of Zoology, The University of Lahore, Sargodha Campus, Sargodha-40100, Pakistan
Umer Ali
Department of Biological Sciences, Tennessee State University, Nashville USA 37209
Muhammad Usman
Department of Zoology, The University of Lahore, Sargodha Campus, Sargodha-40100, Pakistan
Anisa Iftikhar
Department of Biology, Clarkson University, Postdam, USA
Asad Munir
Department of Zoology, University of Sargodha-40100