FORMULATION OF POLYHERBAL CREAM BASED ON PRESENCE OF SECONDARY METABOLITES, ITS ORGANOLEPTIC ASSESSMENT AND THERAPEUTIC EFFECT ON DERMATITIS PATIENTS
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Keywords
Polyherbal Cream, Phytochemical Analysis, Skin Infections, Dermatitis
Abstract
Background and Objective: Dermatitis is a multifactorial skin inflammatory diseases and economic burden due to high cost treatment. This disease decreases the quality of life. The objective of this research is to formulate a local applicant by using plant extracts and to evaluate its effects clinically on patients.
Material and Methods: The plant materials, leaves of Lawsonia inermis, fresh bark of Ficus carica, Carica papaya and Pisidium guajava were collected, extracts prepared, phytochemicals analyzed and cream is prepared by mixing oil phase and aqueous phase. The organoleptic evaluation of cream was done and then by designing the study the cream applied disease patients.
Results: Results was measured after 4 weeks of application of cream and clinical parameters was selected before the study and productive change measured in these like extent area, redness, swelling, crusting, itching. Then SEM of SCORAD values measured which shows the remarkable curing effects.
Conclusion: The plants used in the formulation of cream was found to be promising for the treatment of dermatitis. On the base of results, cream was effective in minimalizing the symptoms like itching, inflammation, skin thickening and dryness. It will improve the quality of life of dermatitis patients.
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Shahlla Umbreen
Institute of Molecular Biology and Biotechnology, The University of Lahore, Pakistan
Farheen Ansari
Institute of Molecular Biology and Biotechnology, The University of Lahore, Pakistan