SYNTHESIS, SPECTRAL CHARACTERIZATION, AND BIOLOGICAL EVALUATION OF SOME LANTHANIDE(III) COMPLEXES OF SCHIFF BASES OF THIOCARBOHYDRAZIDE DERIVATIVES
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Keywords
Lanthanide complexes, α-benzilmonoxime, thiocarbohydrazide, p-bromobenzaldehyde
Abstract
Thiocarbohydrazide-derived α-benzilmonoximethiocarbohydrazie-p-bromobenzaldehyde (HBMT pBB) has been utilized to synthesize and characterize complexes with inner transition metals, namely La(III), Nd(III), Gd(III), Sm(III), Pr(III), Tb(III), Dy(III), Eu(III), Lu(III), and Ce(III). The structural and bonding properties of these complexes were investigated through various analytical techniques, including elemental analysis, physical conductivity measurements, and magnetic susceptibility measurements. Additionally, spectral analyses, encompassing PMR (proton magnetic resonance), FT(IR) (Fourier-transform infrared) Electronic absorption spectra and Powder XRD were employed to gain insights into the complex structures and their bonding nature.
The trivalent metal complexes, formed as a result of these reactions, exhibited a consistent seven-coordinate geometry. To further explore their potential applications, the prepared complexes were evaluated for their antifungal and antibacterial activities against four bacterial species. Specifically, the tested gram-positive strains included B. subtilis (MCC 2010) and S. aureus (MCC 2408), while the gram-negative strains encompassed P. aeruginosa (MCC 2080) and E. coli (MCC 2412). These investigations aimed to shed light on the potential biological efficacy of the synthesized complexes against a diverse range of microorganisms
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Dr. Sharad Sankhe
Professor, Department of Chemistry, Patkar-Varde College, Goregaon West, Mumbai-62, India.
Mr. Pratik Sarvade
PhD scholar, Department of Chemistry, Patkar-Varde College, Goregaon West, Mumbai-62, India