VENTRICULAR TACHYCARDIA IN PATIENTS WITH ARRYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY
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Keywords
Ventricular tachycardia, Arrythmogenic right ventricular cardiomyopathy
Abstract
Objective: This study was conducted to explore Ventricular tachycardia in patients with arrythmogenic right ventricular cardiomyopathy
Materials and methods: A prospective study was conducted at Cardiac Electrophysiology Department, Hayatabad Medical Complex Peshawar Pakistan from 1st January 2015 till 31 December 2020, with 107 patients who suffered from sustained ventricular tachycardia (VT) being examined. Following etiological evaluation, 15 patients were found to have ventricular tachycardia (VT) causing ARVC as per the Modified Task Force Criteria. To better understand this entity in our study, we observed their clinical profile in detail. All the data was analyzed statistically.
Results: A total of 15 patients fulfilled the criterion for inclusion in our study. There were 12 (80%) male patients and 3 (20%) were female patients. Age of the patients ranged from 15 to 55 years whereas mean age at presentation was 30 years. 80% of the patients had abnormal ECG findings.10 patients (66%) had repolarization abnormalities, and 5 (33%) had depolarization abnormality due to Epsilon wave interference. 9 patients who were hemodynamically stable were administered antiarrhythmic drugs. 7 patients reverted to the drugs only, and 2 needed further electric cardioversion due to sinus rhythm failure. Intravenous drugs restored the sinus rhythm with a 78% success rate. In six patients with hemodynamic instability, DC cardioversion was used to reverse the effects of a combination therapy that involved both medical and electric cardioversion. Antiarrhythmic drugs were administered to 9 patients, among them all 6 who successfully terminated VT. Amiodarone was used by 56% of the patients and sotalol was taken by 2 patients. Two patients were treated with a combination of different drugs, including amiodarone, sotalol, and lignocaine. An Automated implantable cardioverter defibrillator (AICD) was implanted in 9 patients.
Conclusion: Ventricular tachycardia frequently occurs in patients with arrythmogenic right ventricular cardiomyopathy and may significantly contribute to morbidity and mortality
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Zahoor Ahmad Khan
Assistant Professor, Cardiac Electrophysiology Department, Hayatabad Medical Complex Peshawar – Pakistan
Javaidullah Khan
Specialist Registrar Cardiac Electrophysiology, HMC, Peshawar - Pakistan
Zahid Aslam Awan
Professor Cardiac Electrophysiology Department, HMC, Peshawar - Pakistan