The Study of the Impact of Gold Nanoparticles and Carbon Tetrachloride on the Liver of Rattus norvegicus
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Keywords
Gold Nanoparticles, Carbon Tetrachloride, Rattus Norvegicus, Liver
Abstract
Gold nanoparticles have been widely studied in nanotechnology for their anti-cancer properties and other potential benefits. In this study, gold nanoparticles were evaluated for their therapeutic effects on the liver injury caused by CCl4 in Rattus Norvegicus. Male rats were induced with liver injury through CCl4 and treated with gold nanoparticles daily for 14 days. To determine the therapeutic effects, biochemical analysis was performed, and after 14 days, the rats were euthanized. The results showed that the rats injected with CCl4 had experienced weight loss and fur color changes, whereas the rats injected with CCl4 and gold nanoparticles had increased weight and normal feeding habits. This suggests that gold nanoparticles have anti-inflammatory effects and can alleviate liver cirrhosis. This study provides evidence for the potential therapeutic applications of gold nanoparticles in liver injury treatment.
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