The effects of three different dosages of Garcinia Cambogia Extract on the atherogenic index of plasma (AIP) and insulin gene expression in T2DM Albino Wistar rats

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Prof. Dr Kashif Rasheed Shaikh, Prof. Dr Kausar Amir, Dr. Shomail Saeed Siddiqui

Keywords

Diabetes Mellitus, Insulin, Cholesterol

Abstract

Introduction
The purpose of this study is to see how Garcinia Camobogia affects the Atherogenic Index of plasma and insulin gene expression in alloxan-induced albino Wistar rats.
Methodology
Albino Wistar rats were obtained from the Open Market/Animal House of the JPMC Karachi Basic Medical Sciences Institute. The researchers followed the standards specified in the NIH Guide for the Care and Use of Laboratory Animals to ensure sufficient housing and treatment of the rats. The rats were housed in stainless steel cages with sawdust bedding, stainless steel feed containers, and plastic drinking bottles with stainless steel nozzles.

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References

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2. Shetty P, Rai M, Ravindran A, Gopalakrishna HN, Pai VR, Kalal BS. Hypoglycemic and hypolipidemic effects of Garcinia cambogia extracts in streptozotocin-nicotinamide induced diabetic rat model. International Journal of Clinical and Experimental Pathology. 2022;15(9):380.
3. Barilee HI, Emine T, Davies G, Edna ON. Evaluation of the Antioxidant, Antidiabetic and Hypolipidemic Potential of Garcinia kola Seed Tincture in Streptozotocin-Induced Diabetic Albino Wistar Rats. Journal of Complementary and Alternative Medical Research. 2022 Dec 15;20(2):12-24.

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Published
Dec 8, 2023

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How to Cite
Prof. Dr Kashif Rasheed Shaikh, Prof. Dr Kausar Amir, Dr. Shomail Saeed Siddiqui. (2023). The effects of three different dosages of Garcinia Cambogia Extract on the atherogenic index of plasma (AIP) and insulin gene expression in T2DM Albino Wistar rats. Journal of Population Therapeutics and Clinical Pharmacology, 30(17), 737-742. https://mail.jptcp.com/index.php/jptcp/article/view/3645
Issue
Vol. 30 No. 17 (2023): JPTCP
Section
Articles
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How to Cite

Prof. Dr Kashif Rasheed Shaikh, Prof. Dr Kausar Amir, Dr. Shomail Saeed Siddiqui. (2023). The effects of three different dosages of Garcinia Cambogia Extract on the atherogenic index of plasma (AIP) and insulin gene expression in T2DM Albino Wistar rats. Journal of Population Therapeutics and Clinical Pharmacology, 30(17), 737-742. https://mail.jptcp.com/index.php/jptcp/article/view/3645