A PROSPECTIVE STUDY ON ISCHEMIC STROKE CAUSED DUE TO COMORBID CONDITIONS, USE OF LMWH AND ITS OUTCOME
Main Article Content
Keywords
.
Abstract
AIM:
- The study aims to detect the effects of co-morbid conditions leading to ischemic stroke.
- sage of LMWH and its outcomes in a tertiary care hospital.
OBJECTIVES:
- To assess the risk among patients in ischemic stroke with co-morbid conditions.
- To assess safety profile, and documented clinical outcomes, in patients prescribed with heparins suffering from Acute ischemic stroke.
MATERIALS AND METHOD:
An observational study was accomplished on inpatients, who were confirmed ischemic stroke throughout 6 months. Patients on LMWH drug therapy were evaluated to know the outcomes and the co-morbid conditions leading to ischemic stroke. The data was collected and documented.
RESULT:
A total of 152 inpatients were observed according to their co-morbid conditions like CVA, DM, HTN, CAD, etc among which the prevalence of hypertension was majorly reported, followed by diabetes in concordance with the addictions like smoking and alcohol abuse, which may a reason for worsening of the condition.
Based on statistical analysis it is proven that comorbid condition indeed shows a significant affects on the progression of the disease by rejecting the null hypothesis.
CONCLUSION:
The patients suffered from co-morbid conditions such as diabetes and hypertension. In the following study 152 inpatients were observed. The collected data showed CVA, CAD and others among which the prevalence of hypertension was majorly reported and was followed by diabetes mellitus. Along with these comorbid conditions, the addictions like smoking and alcohol abuse played a vital role in worsening the stroke due to decreased oxygen supply.
Based on statistical analysis it is proven that comorbid condition indeed shows a significant affects on the progression of the condition by rejecting the null hypothesis. LOW MWH is a major drug used pharmacologically for the cure of TIA, and based upon the collected data it shows desirable outcomes in 99% of cases.
Among the 152 cases observed, its shows negative outcome in two cases by showing bleeding in patients. subjects with excessive blood loss are treated with TXA.
References
2. Robert brown M.D stroke JAN 20 2022
3. Health navigator New Zealand, Stroke last updated, Nov 24 2022.
4. CDC- Centre for disease control and prevention, Stroke, Nov 2 2022.
5. MDPI-International journal of molecular science, Stroke-treatment and pathophysiology Diji
Kuriakose and Zhicheng Xiao, doi: 10.3390/ijms21207609
6. International journal of Pharma research and review, Stroke, pathophysiology and treatment Neema Kanyalet.al, IJPRR 2015; 4(10).
7. NIH National heart lung and blood institute, stroke-symptoms last updated March 24 2022
8. Computed Tomography (CT) Scan, what is a CT scan?, Johns Hopkins medicine.
9. Computed tomography (CT) Scan, Mayo clinic, 20 Jan 2022.
10. Magnetic Resonance Imaging (MRI), diagnosis, NHS services, 13 sept 2022.
11. Magnetic resonance imaging (MRI), Mayo clinic, 4 sept 2021.
12. Electrocardiogram (ECG), NHS services, 7 sept 2021.
13. Electrocardiogram (ECG), Mayo clinic, 19 March 2022.
14. Sunil k. Agarwal, Elsayed Z. Soliman, electrocardiogram (ECG) abnormalities and stroke incidence, 2013;11(7):853-861.
15. Electroencephalogram (EEG), Mayo clinic, 11 may 2022.
16. Farishte Erani and co., electroencephalogram (EEG), might improve diagnosis of acute stroke and large vessel occlusion, 18 sept 2020.
17. Two-dimensional Echocardiogram (2D Echo), types and what they show, Cleveland clinic, 5 Nov 2022.
18. Michael brainin, wolf- dieter heiss; stroke medicine, two dimensional echocardiogram (2D Echo), text book of stroke medicine, Cambridge University press, 10.1017(may 2019).
19. Complete blood picture (CBP), National heart lung and blood institute, NHLBI, NIH (24 March 2022).
20. WoIters kluwer, schemic stroke treatment,Patient education: Ischemic stroke treatment (Beyond the Basics), up to date.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr. Aishwarya Dinakaran
Associate Professor, Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad-501510.
Shaesta Maheen Fatima
Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.
Aleem Unnisa Begum Alias Fatika Begum
Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.
Mohammed Abdul Bari Ahmed
Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.
Misbah Zareen
Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad501510.
Dr. Sudhakara Rao
Professor and HOD, Department of Pharmacy Practice, MRM College of Pharmacy, Chintapally guda, Hyderabad-501510.