THE EFFECTIVENESS OF PREOPERATIVE AND POSTOPERATIVE PARACETAMOL ADMINISTRATION FOR ORTHODONTIC PAIN CONTROL ON PLACEMENT OF ELASTOMERIC SEPARATOR USING VISUAL ANALOG SCALE.A RANDOMIZED CLINICAL TRIAL
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Keywords
Orthodontic Pain, Paracetamol, Separator
Abstract
BACKGROUND-During orthodontic treatment, the most prevalent issue that patients experience is discomfort. NSAIDs is frequently taken as a pain reliever. Many NSAIDs are available in the market which includes aceclofenac, paracetamol, ibuprofen, and celecoxib etc. Paracetamol has been recommended that the best analgesic for orthodontic therapy. It is the safest medication.
AIM- The purpose of this study is to compare the effectiveness of paracetamol when administered before the placement of the separator in one group and after the placement of the separator in another group.
METHODOLOGY- Patients seeking orthodontic treatment were included in this study. The participants were randomly divided into 3 groups. Group 1- control group, Group 2- preemptive group, Group 3-postemptive group. Each tablet was placed in a resealable plastic bag, with a corresponding dose. Each plastic bag was labeled at what time the patient should take the tablet. The tablet was not identifiable as to what it contained, paracetamol or placebo(vitamin B complex).Placebo was used in control group.Posterior separators were placed by the researcher depending on the sample group. The participants recorded their degree of discomfort in four instances of time while at rest, before placement of the separator, and while chewing on anterior biting, and posterior biting. The participants were instructed to take the medicine 1hr before placement and 4hrs after placement of the separator. The participants recorded their degree of pain over a visual analog scale having a marking of 100 mm called VAS SCALE. Kolmogorov- Smirnov test and Shapiro-Wilks test were employed to test the normality of data. Kruskal Wallis Test and post hoc analysis were performed for quantitative variables. The level of significance was fixed at 5% and p ≤ 0.05 was considered statistically significant.
RESULTS-There is no significant difference b/w among all 3 groups at 1 hr before placement. There is a significant difference between preemptive and preemptive groups at rest, before separator placement as well as during anterior and posterior biting at 2hr, at bedtime,4 hr, upon awakening, and 24hrs.
CONCLUSION-This study concluded that the pain increased after orthodontic separator placement and then gradually lessened after 24 hours.
References
2. Karthi M, Anbuslevan GJ, Senthilkumar KP, Tamizharsi S, Raja S, Prabhakar K. NSAIDs in orthodontic tooth movement. Journal of pharmacy & bioallied sciences. 2012 Aug;4(Suppl 2):S304.
3. Shetty N, Patil AK, Ganeshkar SV, Hegde S. Comparison of the effects of ibuprofen and acetaminophen on PGE2 levels in the GCF during orthodontic tooth movement: a human study. Progress in orthodontics. 2013 Dec;14(1):1-5.
4. Abdaljawwad AA, Al-Groosh DH. Effects of various analgesics on pain perception and rate of tooth movement: a randomized controlled clinical study. Journal of Baghdad College of Dentistry. 2022 Jun 15;34(2):37-51.
5. Zarif Najafi H, Oshagh M, Salehi P, Babanouri N, Torkan S. Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial. Progress in Orthodontics. 2015 Dec;16(1):1-9.
6. Long H, Wang Y, Jian F, Liao LN, Yang X, Lai WL. Current advances in orthodontic pain.
International journal of oral science. 2016 Jun;8(2):67-75.
7. Rafeeq RA, Saleem AI, Hassan AF, Nahidh M. Orthodontic pain (causes and current management) a review article. International Medical Journal. 2020;25(3):1071-80.
8. Lin W, Farella M, Antoun JS, Topless RK, Merriman TR, Michelotti A. Factors associated with orthodontic pain. Journal of Oral Rehabilitation. 2021 Oct;48(10):1135-43.
9. Hussain AS, Al Toubity MJ, Elias WY. Methodologies in orthodontic pain management: a review. The open dentistry journal. 2017;11:492.
10. Krishnan V. Orthodontic pain: from causes to management—a review. The European Journal of Orthodontics. 2007 Apr 1;29(2):170-9.
11. Zarif Najafi H, Oshagh M, Salehi P, Babanouri N, Torkan S. Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial. Progress in Orthodontics. 2015 Dec;16(1):1-9.
12. Nik TH, Shahsavari N, Ghadirian H, Ostad SN. Acetaminophen versus liquefied ibuprofen for control of pain during separation in orthodontic patients: a randomized triple blinded clinical trial. Acta Medica Iranica. 2016 Jul 9:418-21.
13. Bird SE, Williams K, Kula K. Preoperative acetaminophen vs ibuprofen for control of pain after orthodontic separator placement. American Journal of Orthodontics and Dentofacial Orthopedics. 2007 Oct 1;132(4):504-10.
14. Chopra S, Rampal V, Chopra A, Jhumat D. An Investigation of the Comparative Effectiveness of Ibuprofen and Paracetamol in the Management of Orthodontic Discomfort. Journal of Coastal Life Medicine. 2023 Feb 22;11:635-41.
15. Alqahtani N, Alwakeel A, Alzamil A, Alturki S, Aldawsari G, Aljabaa A, Albarakati S. Comparison of two analgesics used for pain relief after placement of orthodontic separators. Saudi pharmaceutical journal. 2017 Dec 1;25(8):1169-74.
16. Sudhakar V, Vinodhini TS, Mohan AM, Srinivasan B, Rajkumar BK. The efficacy of different preand post-operative analgesics in the management of pain after orthodontic separator placement: a randomized clinical trial. Journal of pharmacy & bioallied sciences. 2014 Jul;6(Suppl 1):S80.
17. Cheng C, Xie T, Wang J. The efficacy of analgesics in controlling orthodontic pain: a systematic review and meta-analysis. BMC Oral Health. 2020 Dec;20:1-9.
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Tauseef Mohsin
PG Resident, Department of Orthodontics, University of the East, Manila, Philipines
Farheen Akhtar
PG Resident, Department of Conservative dentistry and Endodontics, Hitkarini Dental College, Jabalpur, M.P, India.
Sania Mohsin
PG Resident, Department of Prosthodontics,Crown and Bridge,Mithila Minority Dental College, Darbhanga,India.