GREEN CHEMISTRY STRATEGIES IN DRUG DISCOVERY AND DEVELOPMENT
Main Article Content
Keywords
Green chemistry, Sustainability, Greener solvents, Toxicity reduction
Abstract
Background: The drug discovery and development process traditionally involve the use of hazardous chemicals, high energy consumption, and generates significant waste, leading to adverse environmental impacts. To address these concerns, the integration of green chemistry principles has gained attention in the field.
Aim: The purpose of this study was to evaluate and discuss the implementation of green chemistry strategies in the field of drug discovery and development.
Method: Green chemistry strategies included the use of computational methods and high-throughput screening to prioritize compounds, the utilization of greener solvents and reaction conditions, the implementation of innovative techniques like flow chemistry to reduce waste, and the design of molecules with reduced toxicity and improved biodegradability.
Result: By adopting green chemistry strategies, drug discovery and development processes can minimize resource consumption, waste generation, and the use of hazardous chemicals. This approach also leaded to improved efficiency, safety, and sustainability.
Conclusion: The incorporation of green chemistry principles in drug discovery and development offers significant potential for the pharmaceutical industry to develop safer, more effective drugs while reducing their environmental impact. Implementing these strategies promotes a greener and more sustainable future for drug development.
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Mohammed Saeed Alshehri
Pharmacist in public security-MOI, King Saud University.