FORMULATION AND CHARACTERIZATION OF MAGNETIC NANOPARTICLES OF TAMOXIFEN CITRATE
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Keywords
MNP’s, Cancer, Tamoxifen citrate, Breast Cancer, TMX.
Abstract
In this work, iron oxide MNPs was effectively prepared by co-precipitation method that is effortless and facilitates of integrating. The main aim of this method is that a huge measure of NPs can be set up. At that point, these nanoparticles were functionalized with arginine to us for biomedical applications because of their great similarity. The surface functionalization of NPs is obviously worthwhile attributable to shield them from agglomeration and furthermore limit the additional cell cooperation. Additionally, it makes option of biomolecules conceivable. For example, amino acids can be utilized to form with corrosive gatherings of TMX. From that point forward, TMX was formed to NPs by the expansion of EDC and NHS. The morphology and size of them were researched by the TEM. It very well may be seen that these NPs had a round shape with consistency in morphology.
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Kalpeshkumar S. Wagh
Research Scholar, Department of Pharmaceutics, Oriental University, Indore, Madhya Pradesh, India.
Dr.Namrata Singh
Faculty of Pharmacy, Department of Pharmacognosy, Oriental University, Indore, Madhya Pradesh, India.