FORMULATION AND EVALUATION OF PRONIOSOMAL GEL FOR DOXYCYCLINE
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Keywords
Proniosomal gel, antifungal drug, topical drug delivery
Abstract
Proniosome gels' gives beneficial outcomes on degenerative joint sickness, there is a ton of interest in their utilization in transdermal drug conveyance frameworks. The reason for the ongoing review was to make and portray a proniosome of the NSAIDS drug, Doxycycline which might ship these prescriptions to the objective site all the more successfully and furthermore settle the issue with oral medicine organization. The viability of proniosome as another lipid for the effective dissemination of Doxycycline has been evaluated in the ongoing examination. By changing the convergence of phospholipids, cholesterol, Tween 60, and ethanol, and ph buffer7.4, proniosomes were upgraded. The plan of proniosome containing ethanol, cholesterol, and soy lecithin was moved along. Results: The best outcomes were gotten utilizing the F4 plan, which created round, unilamellar vesicles with a smooth surface when described. Proniosomes have been proposed as viable transporters for the skin organization of the medicine Doxycycline
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km saman Fatma
Research scholar kailash institute of pharmacy and management, Gida gorakhpur Uttar Pradesh
Mrs. priyanka Maurya
Associate Prof. Dept of pharmaceutics, Kailash institute of pharmacy and management, Gida , Gorakhpur Uttar Pradesh
Dr .Jai Narayan Mishra
Director kailash institute of pharmacy and management Gida Gorakhpur Uttar Pradesh