EVALUATING SAFETY AND PAIN CONTROL: INTRAVENOUS PARACETAMOL VS. PENTAZOCINE IN ABDOMINAL SURGICAL PROCEDURES
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Keywords
Postoperative Pain Management, Abdominal Surgery, Visual Analog Scale, Adverse Events, Rescue Analgesia
Abstract
Background: Postoperative pain management is necessary for patient recovery after abdominal surgery. The study aimed to compare the efficacy and safety of intravenous paracetamol and pentazocine for postoperative pain control in adults undergoing abdominal surgery.
Methods: A total of 80 patients undergoing surgery at Department of Surgery, Varun Arjun Medical College & Rohilkhand Hospital were randomly allocated into two groups: Group A (n=40) received intravenous paracetamol, and Group B (n=40) received pentazocine. Visual Analog Scale (VAS) scores for pain, adverse events, and the need for rescue analgesia were evaluated.
Results: Group A reported significantly lower VAS scores at most time points except at 12 hours. Respiratory depression was significantly lower in Group A (p=0.045). The need for rescue analgesia was lower in Group A but was not statistically significant (p=0.059).
Conclusion: Intravenous paracetamol is more effective and safer than pentazocine for postoperative pain management in adult abdominal surgeries. Further studies are warranted to confirm these findings.
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Dr. Atul Tandon
Associate Professor, Department of General Surgery, Varun Arjun Medical College & Rohilkhand Hospital
Dr. Gaddam Thapasya Reddy
Associate Professor, Department of Obstetrics & Gynaecology, Varun Arjun Medical College & Rohilkhand Hospital
Dr. Jitendra Agrawal
Assistant Professor, Department of Orthopedic surgery, Varun Arjun Medical College & Rohilkhand Hospital
Dr. Vishnu Kumar Sharma
Professor, Department of General Surgery, Varun Arjun Medical College & Rohilkhand Hospital,
Dr. Arushi Saxena
Assistant Professor, Department of Anaesthesiology, Varun Arjun Medical College & Rohilkhand Hospital
Masuram Bharath Kumar
Assistant Professor, Department of Pharmacology, Varun Arjun Medical College & Rohilkhand Hospital