‘’MANAGEMENT OF PAEDIATRICS INTUSSUSCEPTION IN TERTIARY CARE CENTRE’’

Main Article Content

Dr. Rohit Mittal
Dr. Pramila Sharma
Dr. Ramesh Tanger
Dr. Ravindra Sevar

Keywords

Air enema, Clinical manifestations, Epidemiology, Intussusception

Abstract

Background- Intussusception is a medical emergency that occurs in children when a part of the bowel 'telescopes' (folds) into another part of the bowel. This causes pain, vomiting, and obstruction, preventing passage. If left untreated, the bowel can perforate, resulting in passage of its contents into the abdominal cavity, causing further complications. In rare cases, these events can cause death. Prompt diagnosis and management reduces associated risks and the need for surgery.


Aims and objective- ’Management of paediatrics intussusception in tertiary care centre’.


Methods- This prospective study included paediatric patients with acute intussusception admitted to the Department of Paediatric Surgery, SMS medical college and hospital Jaipur, from January 2023 to June 2023 for six months periods. The inclusion criteria were- age 0–10 years, diagnosed with intussusception. The exclusion criteria were- combined with other surgical acute abdominal conditions, history of previous abdominal surgery and missing data. All children were diagnosed by abdominal ultrasound, showing a “target ring sign” or a “concentric circle sign” in the transverse section and a “sleeve sign” in the longitudinal section. The clinical data of all children were prospectively collected from historical medical recorders, including sex, age, month of onset, disease duration, etiology, clinical symptoms, intussusception depth, treatments, outcomes, and relapses. Statistical analysis SPSS 19.0 (IBM, Armonk, NY, USA) was used for data analysis. Continuous data were expressed as means±standard deviation and analysed using Student’s t-test. Categorical data were expressed as n (%) and analysed using the chi-square test. Two-sided P-values5 years old.


Results- total 100 patients included in this study, males are most commonly affected than female, M/F =3/1 in this study. Most of the patient affected in age group of 12-24 months of age group. Most of the patient’s hospital visit time after symptoms are 12-24 hours. The disease onset was most frequent in April (25%), but it occurred throughout the time without an obvious central tendency. Among the 100 children, 86 (86%) had abdominal pain (young infants presented as paroxysmal crying), 50% have vomiting, and 10 patients (10%) had a typical triad of intussusception (abdominal pain +bloody stools +abdominal mass). Most of the patient have no any etiology for disease found, 10% have history of diarrhoea, 15% have vaccination history, 10% have infection history found. The average intussusception depth was 4.0±1.4 cm, with the shortest being 1.1 cm, the longest being 9.0 cm, and the median being 3.9 cm. 15% were treated with enema reduction, and those not relieved by the initial enema were given repeat air enema. Those who still could not be reduced by delayed enemas were considered as cases of reduction failure. The cases of reduction success were 15%. There were 5 cases of reduction failure, which were all successfully reduced by conversion to surgical reduction. Among them, one case of jejuno-ileal, 10% ileo-ileal and 9% colo-colic types. Most cases are ileo-colic types. No significant abnormalities were found during the intraoperative probing from the ileocecal to the proximal intestinal canal 1.5 cm in length. out of 100 patients, 2 patients come with recurrence of disease within one years. out of surgically repaired patients, two patients have wound infection and one patient goes into paralytic ileus, which managed conservatively.


Conclusions- Paediatric acute intussusception is common. There was no obvious etiology. The clinical manifestations are mostly atypical. Abdominal pain is the most common complaint. Air enema reduction is an effective treatment

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References

1. Loukas M, Pellerin M, Kimball Z, de la Garza-Jordan J, Tubbs RS, Jordan R. Intussusception: an anatomical perspective with review of the literature. Clin Anat. 2011; 24:552–61.
2. Edwards EA, Pigg N, Courtier J, Zapala MA, MacKenzie JD, Phelps AS. Intussusception: past, present and future. Pediatr Radiol. 2017; 47:1101–8.
3. Applegate KE. Intussusception in children: evidence-based diagnosis and treatment. Pediatr Radiol. 2009;39(Suppl 2):140–3.
4. Ko HS, Schenk JP, Troger J, Rohrschneider WK. Current radiological management of intussusception in children. Eur Radiol. 2007; 17:2411–21.
5. Tate JE, Simonsen L, Viboud C, Steiner C, Patel MM, Curns AT, et al. Trends in intussusception hospitalizations among US infants, 1993–2004: implications for monitoring the safety of the new rotavirus vaccination program. Pediatrics. 2008; 121:e1125–32.
6. Buettcher M, Baer G, Bonhoeffer J, Schaad UB, Heininger U. Three-year surveillance of intussusception in children in Switzerland. Pediatrics. 2007; 120:473–80.
7. Yang G, Wang X, Jiang W, Ma J, Zhao J, Liu W. Postoperative intussusceptions in children and infants: a systematic review. Pediatr Surg Int. 2013; 29:1273–9.
8. Waseem M, Rosenberg HK. Intussusception Pediatr Emerg Care. 2008; 24:793–800.
9. Simanovsky N, Issachar O, Koplewitz B, Lev-Cohain N, Rekhtman D, Hiller N. Early recurrence of ileocolic intussusception after successful air enema reduction: incidence and predisposing factors. Emerg Radiol. 2019; 26:1–4.
10. Jung H, Kim HJ, Choi ES, Lee JY, Park KS, Cho KB, et al. Effectiveness of oral phloroglucinol as a premedication for unsedated esophagogastroduodenoscopy: a prospective, double-blinded, placebo-controlled, randomized trial. PLoS ONE. 2021;16: e0255016.
11. Yap Shiyi E, Ganapathy S. Intussusception in Children presenting to the Emergency Department: an asian perspective. Pediatr Emerg Care. 2017; 33:409–13.
12. Savoie KB, Thomas F, Nouer SS, Langham MR Jr, Huang EY. Age at presentation and management of pediatric intussusception: a Pediatric Health Information System database study. Surgery. 2017; 161:995–1003.
13. Justice FA, Auldist AW, Bines JE. Intussusception: trends in clinical presentation and management. J Gastroenterol Hepatol. 2006; 21:842–6.
14. Ntoulia A, Tharakan SJ, Reid JR, Mahboubi S. Failed Intussusception reduction in children: correlation between Radiologic, Surgical, and pathologic findings. AJR Am J Roentgenol. 2016; 207:424–33.
15. Jain S, Haydel MJ. Child Intussusception. StatPearls. Treasure Island (FL)2022.
16. Kaemmerer E, Tischendorf JJ, Steinau G, Wagner N, Gassler N. Ileocecal intussusception with histomorphological features of inflammatory neuropathy in adenovirus infection. Gastroenterol Res Pract. 2009; 2009:579501.
17. Bogdanovic M, Blagojevic M, Kuzmanovic J, Jecmenica D, Alempijevic D. Fatal intussusception in infancy: forensic implications. Forensic Sci Med Pathol. 2019; 15:284–7. Li et al. BMC Pediatrics (2023) 23:143 Page 6 of 6
18. Guo WL, Zhang SF, Li JE, Wang J, Wang LJPO. Association of Meteorological Factors with Pediatric Intussusception in Subtropical China: A 5-Year Analysis. 2014;9: e90521-.
19. Kimia AA, Williams S, Hadar PN, Landschaft A, Porter J, Bachur RG. Positive guaiac and bloody stool are poor predictors of intussusception. Am J Emerg Med. 2018; 36:931–4.
20. Kimia AA, Hadar PN, Williams S, Landschaft A, Monuteaux MC, Bachur RG. Variation in the presentation of Intussusception by Age. Pediatr Emerg Care. 2020; 36:372–7.
21. Bartocci M, Fabrizi G, Valente I, Manzoni C, Speca S, Bonomo L. Intussusception in childhood: role of sonography on diagnosis and treatment. J Ultrasound. 2015; 18:205–11.
22. Hryhorczuk AL, Strouse PJ. Validation of US as a first-line diagnostic test for assessment of pediatric ileocolic intussusception. Pediatr Radiol. 2009; 39:1075–9.
23. Charles T, Penninga L, Reurings JC, Berry MC. Intussusception in children: a clinical review. Acta Chir Belg. 2015; 115:327–33.
24. Sadigh G, Zou KH, Razavi SA, Khan R, Applegate KE. Meta-analysis of Air Versus Liquid Enema for Intussusception reduction in children. AJR Am J Roentgenol. 2015;205: W542–9.
25. Lautz TB, Thurm CW, Rothstein DH. Delayed repeat enemas are safe and cost effective in the management of pediatric intussusception. J Pediatr Surg. 2015; 50:423–7.
26. Chassany O, Bonaz B, Bruley DESVS, Bueno L, Cargill G, Coffin B, et al. Acute exacerbation of pain in irritable bowel syndrome: efficacy of phloroglucinol/ trimethyl-phloroglucinol. A randomized, double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2007; 25:1115–23.
27. Yu Y, Qin X, Yan S, Wang W, Sun Y, Zhang M. Non-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review. Onco Targets Ther. 2015; 8:3707–13.
28. Kim JH, Lee JS, Ryu JM, Lim KS, Kim WY. Risk factors for recurrent intussusception after fluoroscopy-guided Air Enema. Paediatric Emerg Care. 2018; 34:484–7.
29. Justice FA, Nguyen LT, Tran SN, Kirkwood CD, Thi NT, Carlin JB, et al. Recurrent intussusception in infants. J Paediatric Child Health. 2011;47: 802–5