QUALITATIVE PHYTOCHEMICAL INVESTIGATION AND EVALUATION OF ANTHELMINTIC ACTIVITIES OF ACALYPHA INDICA LEAF FRESH EXTRACT
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Keywords
Acalypha indica, phytochemical investigation, anthelmintic activities, pheretima posthuma
Abstract
Since many traditional reports shows that, the leaves of Acalypha indica contains anthelmintic activity, the fresh extract of Acalypha indica leaves was collected and it is subjected to show the anthelmintic activity and its activities are compared with the marketed standard one (Albendazole suspension). Anthelmintic activity is nothing but killing or expelling the infesting worms. For this, the entire plant of Acalypha indica was collected and extracted, and involved in the phytochemical investigation. Earth worms of pheretima posthumawas used to estimate the anhelmitic activity of the Acalypha indica, the time taken for paralysis (min) and the time taken for death of the worms are recorded and they are compared with the Standard albendazole suspension’s action. The acalypha indica shows better anthelmintic activity as the standard one.
References
2. Dhar DN, Sharma RL and Bansal GC, Gastrointestinal nematodes in sheep in Kashmir. Vet.parasitol volume 11, page no 271-7.
3. Aswar manoi, aswar urmila, watkar bhagyashri et al. anthelmintic activity of ficus bengalensis, In. j.green pharm page no 170-173.
4. Satyavati GV, Raina MK, and Sharma M, Medicinal plant of india. Vol.I. Indian council of med. Res, New Delhi, india page no 201-06
5. Akhtar MS, Zafar Iqbal, Khan MN, and Muhammad Latf. Anthelmintic activity of medicinal plants with particular reference to their use in animals in indo Pakistan subcontinent. Small ruminants res volume 38, page no 99-107.
6. Kirtikar KR, and Basu BD, In.Medicinal plant volume III, international book distributors, dehradun, india, page no; 2262-2263.
7. Annie S, Rajendran K, Ramgopal B, Dineshkumar C, Neutralization potential of viper russelli (Rusell’s viper) venom by ethnol leaf extract of acalypha indica journal ethonapharmacology page no 267-73.
8. Bedon E, Hatfield GM, An investigation of antiviral activities of phodophyllum peltum volume 45(6).
9. Suresh reddy J, Rajeshwara rao p, Mada AR, wound healing effects of hellotropium indicum, plumbago zeylanicum and acalypha indica in rats. Journal of ethnopharmacology 2002: volume 79:249-51.
10. Ruche GM, Majekodunmi, Ramya, Gowri BV, Hussain A, Suad Khamis SB, Antioxidant capacity of some edibile and wound healing plants in oman. Food chemical 2007: 101; page no. 465-70.
11. Mohana vamsi N, Vengat sunilkumar M, Kodandaram N, Padmanbha reddy, Evaluation of anti-inflammatory activity of acalypha indica. Ind.phharm 2008. Volume 07, page no 89-91.
12. Singh DAP, Raman M, Saradha V, Jayabharathi, Acarcidal property of kuppaimeni against natural psoroptes cuniculi infestion in broiler rabbits. In. J animal scince 2004: 74(10); page no 1003-6.
13. Das AK, Ahmed F, Biswas NN, Dev S, Masud MM, diuretic activity of acalypha indica. Dhaka uni J pharm Sci 2005; (4)1-2.
14. Govindarajan M, Jabanesan A, Reetha D, Anisath R, PUshpanathan T, antibacterial activity of acalypha indica L, Eur Rev med pharmacol sci. 2008; volume 12(5): page no 299-32.
15. Nadkarni KM, Medicinal plants of india 2004 edition, Reprint publication, Dehradun, india page no 10-11.
16. Kokate CK, Practical pharmacognosy, 4th edition, vallabha prakashan, New delhi page no 149-156.
17. Khandelwal KR, Practical pharmacognosy technique and experiments, second edition nirali prakashan, pune page no 149-56
18. Vidyarthi RD, A textbook of zoology, 14th edn, chand and Co. press, new delhi page no 329-31.
19. Thorn GW, et al Harrison’ principles of internal medicine, MC grew hill, NEW York. Page no 1088-90.
20. Deore SL, Khadabadi ss, Kamdi KS. et al. In vitro anthelmintic activity of cassia torra. In. J Chem Tech Res 2009; volume 1; page no 177-179.
21. Vigar Z, Atlas of medical parasitology, second edn. Publishing house, Singapore. Page no 216-18.
22. Ajaiyeoba EO, Onocha PA, Olarenwaju OT. In-vitro anthelmintic properties of buchholzia coriaceae and gynandropsisgynandra etract pharm biology 2001: 39; page no 217-220.
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S.A.Vadivel
Research Scholar, School of Pharmaceutical Science,Vels university, Chennai.
G.Sridhar
Department of Pharmaceutics, Sri Balai Vidyapeeth University, Pondicherry
J.Atchaya
Student, 3Smt Gandhimathi College of Pharmacy, Thiruvannamalai, Tamilnadu