ANALYSIS ON THE ANALYTICAL EVALUATION OF DRUG
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Keywords
Diabetes, Simultaneous, Drug, Validation, Insulin, absorbance
Abstract
Type 2 diabetes (T2D), often known as adult-onset diabetes, is a type of diabetes marked by high blood sugar, insulin resistance, and insulin deficiency. The main aim of the study is Analysis on The Analytical Evaluation of Drug. Identification test for Alogliptin Benzoate and MET Hydrochloride was carried out by using IR Spectroscopy and UV absorbance Spectra. The main aim of this research project was to develop and validate the analytical method for simultaneous estimation of MET and AGP by RP-HPLC.
References
2. Magdy MA, Ali NW, Taha AA, Elgebaly AM, Farid NF. Different chromatographic methods for determination of alogliptin benzoate, MET hydrochloride, and metformin impurity in bulk and pharmaceutical dosage form. Journal of separation science. 2021 Feb;44(4):833-42.
3. Anumolu PD, Sunitha G, Priyanka B, Mounika G, Shilpa A. Analytical Qbd Approach First Order Model-Robust Rp-Hplc Method for Simultaneous Assessment of Alogliptin and Metformin.
4. Rana K, Sharma P. Analytical method development and validation for the simultaneous estimation of metformin hydrochloride and alogliptin by rp-hplc in bulk and tablet dosage forms. Research Journal of Science and Technology. 2021 Apr 1;13(2):111-8.
5. Patel HP, Patel DP, Christian JR, Shah PA, Patel KG. Box-Behnken Design Assisted Protein Precipitation Optimization for Simultaneous Determination of Metformin Hydrochloride and Alogliptin Benzoate in Plasma along with Pharmacokinetic Application. Indian Journal of Pharmaceutical Sciences. 2021 Aug 31;83(4):785-93.
6. Sultana N, Rizwana I. Development and validation of stabilty indicating RP-HPLC method for simultaneous estimation of metformin and Alogliptin in bulk and tablet dosage form. Pharma Innovation. 2018; 7:319-24.
7. Rendell M, Drincic A, Andukuri R. Alogliptin benzoate for the treatment of type 2 diabetes. Expert Opinion on Pharmacotherapy. 2012 Mar 1;13(4):553-63.
8. Saisho Y. Alogliptin benzoate for management of type 2 diabetes.Vascular health and risk management. 2015; 11:229.
9. Klepser TB, Kelly MW. Metformin hydrochloride: an antihyperglycemic agent. American journal of health-system pharmacy. 1997 Apr 15;54(8):893-903.
10. Hariharan ME, Rajan SS, Srinivasan R. Structure of metformin hydrochloride. Acta Crystallographica Section C: Crystal Structure Communications. 1989 Jun 15;45(6):911-3.
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