THE IMPACT OF MUSIC THERAPY ON ENHANCING COGNITIVE FUNCTION AND THE LEVELS OF BRAINDERIVED NEUROTROPHIC FACTOR IN THE PLASMA OF SCHIZOPHRENIC PATIENTS WITH RISPERIDONE TREATMENT

Mikael Sri Pabilang; Andi Jayalangkara Tanra; Kristian Liaury; Andi Alfian Zainuddin; Erlyn Limoa; Irfan Idris; Saidah Syamsuddin; Sonny T. Lisal

doi:10.53555/jptcp.v30i16.2555

Mikael Sri Pabilang
Andi Jayalangkara Tanra
Kristian Liaury
Andi Alfian Zainuddin
Erlyn Limoa
Irfan Idris
Saidah Syamsuddin
Sonny T. Lisal

Keywords

Schizophrenia, Music Therapy, Risperidone, Cognitive Function, Plasma BDNF

Abstract

This study aimed to investigate the effect of music therapy on the cognitive function and plasma BDNF levels of schizophrenia patients undergoing risperidone therapy. The study utilized quasi-experimental research and divided the 45 subjects into a treatment group and a control group. The treatment group received risperidone therapy and active and receptive music therapy for 4 weeks/12 sessions, while the control group received only risperidone therapy. Cognitive function was measured using the MoCA-Ina scale, and plasma BDNF levels were also measured. The study found that there was a significant increase in the MoCA-Ina score in both the treatment and control groups, but the treatment group had a higher increase. Additionally, the treatment group showed a significant increase in plasma BDNF levels, while the control group showed a decrease. Comparisons between the two groups showed that the addition of music therapy improved cognitive function, especially in the memory and abstraction domains. Furthermore, there was a significant correlation between changes in MoCA-Ina scores and plasma BDNF levels. Overall, combining music therapy with risperidone therapy can enhance the quality of life of schizophrenia patients by improving their cognitive function.

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Published

Aug 16, 2023

DOI: https://doi.org/10.53555/jptcp.v30i16.2555

How to Cite

Mikael Sri Pabilang, Andi Jayalangkara Tanra, Kristian Liaury, Andi Alfian Zainuddin, Erlyn Limoa, Irfan Idris, Saidah Syamsuddin, & Sonny T. Lisal. (2023). THE IMPACT OF MUSIC THERAPY ON ENHANCING COGNITIVE FUNCTION AND THE LEVELS OF BRAINDERIVED NEUROTROPHIC FACTOR IN THE PLASMA OF SCHIZOPHRENIC PATIENTS WITH RISPERIDONE TREATMENT. Journal of Population Therapeutics and Clinical Pharmacology, 30(16), 620-629. https://doi.org/10.53555/jptcp.v30i16.2555

Issue

Vol. 30 No. 16 (2023): JPTCP

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