Correlation between H. pylori infection and COVID-19 among a sample of dental students
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Keywords
Helicobacter pylori, Coronavirus 19, Gastrointestinal tract
Abstract
COVID-19 infection, the most prevalent deadly pandemic in the world, has been correlated to the highly prevalent Helicobacter Pylori (H.P.) infection which is considered a major cause for gastric carcinoma and it seems to be an important risk factor that predisposes and augments the course of COVID-19 infection, via increasing the expression of angiotensin-converting enzyme-2 receptors in the gastrointestinal tract, to which COVID- 19 binds to enter the cell, causing gastrointestinal symptoms during the course of the disease. The aim of this study was to investigate any possible correlation between H. pylori infection and COVID-19 among a sample of dental students, at the faculty of Dentistry, Fayoum University, Egypt. Methods & Subjects: This study was carried out from October to November, 2022 among a sample of 100 dental students. Those who reported the characteristic symptoms of COVID-19 infection and whose infection was confirmed by nasopharyngeal (NS) PCR-RT swabs, were included in the study. All students were screened for anti- H.P. using saliva samples, analyzed with an enzyme-linked immunosorbent assay (ELISA). All were evaluated for manifestations of COVID-19 infection, severity of the course, hospitalized days because of the virus and outcome of the disease process.
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Christine Mikhail
Lecturer of Oral Medicine and Diagnosis, Department of Oral Medicine, Diagnosis and Periodontology, Faculty of Dentistry, Fayoum University, Fayoum, Egypt
Samia El-Shishtawy
Lecturer of Oral Medicine and Diagnosis, Department of Oral Medicine, Diagnosis and Periodontology, Faculty of Dentistry, Fayoum University, Fayoum, Egypt
Marwa El Nawawy
Lecturer at Department of Oral Medicine, Diagnosis and Periodontology, Faculty of Dentistry, Cairo University, Cairo, Egypt
Layla Hafed
Assistant Professor of Oral and Maxillofacial Pathology, Faculty of Dentistry, Saba University, Sana’a, Yemen
Seham Hazem El-Ayouti
Lecturer of Oral and Maxillofacial Pathology, Faculty of Dentistry, Cairo University, Egypt
Nada Noureldin
Lecturer of Oral and Maxillofacial Pathology, Cairo University
Sally Ibrahim
Associate professor of oral and maxillofacial pathology, Faculty of dentistry, fayoum University, Fayoum, Egypt
Sahar El Refai
Assistant Professor of Oral Pathology, College of Dentistry, Princess Nourah Bint Abdulrahman University,
Riyadh, KSA
Rania Hassan Shalaby
Lecturer of Oral Medicine and Diagnosis, Department of Oral Medicine, Diagnosis and Periodontology, Faculty of Dentistry, Fayoum University, Fayoum, Egypt