Knowledge And Perception The Among Dental Surgeons About A Periodontal Disease As A Risk Factor For Covid-19 Illness : A Web Based Questionnaire Study
Main Article Content
Keywords
Periodontal disease, COVID-19 illness, Dental specialists
Abstract
INTRODUCTION: A Periodontal disease (PD) composes a group of diseases comprising inflammatory aspects of the host and dysbiotic events that impinge the periodontal tissues and could have systemic significances. Discrete factors and comorbidities have been closely accomplices with PD such as diabetes, aging, hypertension etc., although, elementary mechanisms or causal correlations have not been authorized completely. Fascinatingly, these same factors have been extensively correlated with progression of severely graded form of coronavirus disease 2019 (COVID-19), an illness caused by coronavirus SARS-CoV-2. Since inflammatory and dysbiotic factors as well as comorbidities impinge the systemic health, it is feasible that periodontal status illustrate the possiblerisk of complications of COVID-19.
AIMS: To evaluate the Knowledge and perception among the dental surgeons about a Periodontal disease as a risk factor for covid-19 illness : a web based questionnaire study.
SETTINGS AND DESIGN: A Questionnaire web based survey
METHODS AND MATERIAL: Survey consists of 21 questions related to knowledge and awareness about corona virus and periodontal disease as a possible risk factor for covid-19 illness was conducted and evaluated using percentage among 312 participants (195 females 117 males).
RESULTS: A total of 312 participants responded to the questionnaire. 67.1% had sufficient knowledge on the receptors that has high affinity for covid-19 disease, 81.7% dental surgeons had knowledge on periodontal disease that escalate risk for covid-19 related respiratory breakdown .46.8% and 21.9% had knowledge on pro inflammatory cytokine IL-6 and Th 17 enacts a considerablepart in the pathogenesis of covid-19 and periodontitis.
CONCLUSION: The study findings showed adequate awareness about corona virus and simultaneously showed inadequate awareness towards periodontal pathology as a hazardous factor for covid-19 illness among dental surgeons.
References
2.Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate surfaces? A systematic review. BMC Infect Dis 2006;6:130.
3. Zhou P, YangXL, WangXG, Hu B, Zhang L, ZhangWet.al., A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020.
4. Xian Penget.al., Transmission routes of 2019-nCoV and controls in dental practice. International Journal of Oral Science (2020) 12:9
5. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020.
6. Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS. J Virol 2020.JVI.00127-00120.
7. Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, et al. Angiotensin converting enzyme II is a functional receptor for the SARS coronavirus. Nature 2003;426(6965):450–4.
8. Wang D, Hu B, Hu C, Zhu F, LiuX, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020.
9. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020.
10. VaibhavSahnia ,Shipra Gupta et.al., COVID-19 & Periodontitis: The cytokine connection a Panjab University, Chandigarh, medical hypotheses, 28 May 2020.
11. Hantak, M. P., Qing, E., Earnest, J. T. & Gallagher, T. Tetraspanins: architects of viral entry and exit platforms. J. Virol. 93, e01429–e01417 (2019).
12. Hoffmann, M. et al. The novel coronavirus 2019 (2019-nCoV) uses the SARS- coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells. Preprint at https://www.biorxiv.org/content/10.1101/2020.01.31.929042v1.full (2020).
13. Zhao, Y. et al. Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov. Preprint at https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1 (2020).
14 Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med 2020;382(13):1199–207.
15. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020.
16. Z. Badran, et al., Periodontal pockets: A potential reservoir for SARS-CoV-2? Medical Hypotheses 143 (2020) 109907.
17. Jahanshahlu L, Rezaei N. Monoclonal antibody as a potential anti-COVID-19. Biomed Pharmacother.Published online June 4, 2020. 2020;129:110337.
18. Wu D, Yang XO. TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib. J MicrobiolImmunol Infect 2020. https://doi.org/10. 1016/j.jmii.2020.03.005.
19. Sorsa T, Alassiri S, Grigoriadis A, et al. Active MMP-8 (aMMP-8) as a grading and staging biomarker in the periodontitis classification. Diagnostics (Basel) 2020;10(2):61
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.