ASSOCIATION BETWEEN SLEEP APNEA AND GLAUCOMA: A SYSTEMATIC REVIEW
Main Article Content
Keywords
sleep apnea, glaucoma, prisma, perimetry, sonography, optical
Abstract
ABSTRACT:
There has been an ongoing debate in the literature as to whether sleep apnea is associated with
glaucoma. While certain studies have established a link between sleep apnea and normal-
tension glaucoma (NTG) and/or open-angle glaucoma (OAG), other studies have found no
such association. To address this issue, we conducted a systematic review to determine whether
there is a significant positive correlation between obstructive sleep apnea syndrome (OSAS)
and the prevalence of glaucoma.
METHODOLOGY:
All studies including the association between Sleep Apnea and Glaucoma were included in the
study. We only included studies that defined OSA (Obstructive Sleep Apnea) using the AHI
(Apnea Hypopnea Index) via polysomnography or home sleep apnea testing (HSAT/polygraph).
Additionally, we included studies that utilized at least one of the following ophthalmic
examination techniques to assess glaucoma: measurement of intraocular pressure (IOP), optical
coherence tomography (OCT) imaging, sonography, and perimetry for measuring the visual field (VF).
RESULT:
The study was conducted by PRISMA (Preferred Reporting Item for Systematic Review and
Meta-Analysis) 2020 Checklist. This systematic review was conducted and reported according to
Cochrane Handbook and PRISMA statement. The database PubMed, Scopus, and Embase was
thoroughly searched, resulting in the retrieval of 2471 articles from various databases, and 6
additional articles were added through the snowballing method. Out of these, 1800 articles
were eliminated due to duplicates. 677 articles were screened, and 39 were excluded because
they were in languages other than English, leaving 638 articles for the title and
abstract screening. Ultimately, 38 articles were included in the full-text screening.
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Gaurav Mishra, King George's Medical University
Professor
Public Health Dentistry
Swarupa Paul, Career Post Graduate Institution of Dental Sciences
Prosthodontics
Mohd Umar, Career Post Graduate Institution of Dental Sciences
Senior Lecturer
Prosthodontics
Abhishek Katiyar, Career Post Graduate Institution of Dental Sciences
Senior Lecturer
Prosthodontics
Vinay Gupta, King George's Medical University
Professor & Head
Public Health Dentistry
Siddharth David
Senior Lecturer, Dept. Of Public Health Dentistry. Babu Banarasi Das College of Dental Sciences.