Formulation And Characterisation of Nanosilver-Chitosan Biocomposite
Main Article Content
Keywords
Mouthwash, Tamarindseed, chitosan, stains, eruption, decay.
Abstract
Background: Green synthesis of nanoparticles is gaining popularity. When this eco-synthesis of nanoparticles is mediated by commonly available natural resources like tamarind seed, it can combine with other natural products easily to give composite materials with many advantages.
Aim: To formulate, synthesize and assess the antimicrobial and anti-inflammatory property of bionanocomposite being incorporated in silver nanoparticles and chitosan.
Materials and Methods: Silver nanoparticles are prepared by adding tamarind seed and converted as Nanocomposite by homogeneously mixing with chitosan. The anti-inflammatory and antimicrobial property of the prepared bio-nanocomposite is evaluated by assessment of protein denaturation and zone of inhibition against most common oral pathogens respectively.
Results: Anti Inflammatory activity measured by Bovine Serum Assay and Egg Albumin Assay showed that the 75% of protein denaturation was inhibited by 50 microlitre of the prepared Bionanocomposite.In Anti microbial activity,The maximum zone of inhibition of common oral pathogens like S.mutans,S.aureus,E.faecalis and C.albicans is 100 microlitre of concentration from the prepared Nanocomposite.
Conclusion: The study was successful in formulating a Nanocomposite material which is highly eco friendly with less toxicity.This novel Biomaterial can be formulated as Mouthwash in future which mainly focuses on preventing tooth decay and promoting the health of gums.
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