Preparation Of Rod and Spherical Shaped Hydroxyapatite for Tissue Regeneration Application
Main Article Content
Keywords
Hydroxyapatite, Tissue engineering, Cuttlefish, Biocompatible, Bone, Osteoconductive
Abstract
The fundamental goal of current biomaterial research is to replace broken bones with affordable bioactive and biocompatible materials. In the current study, bone powder from the cuttlefish was employed as a precursor in the silicon oil bath-mediated precipitation method to create hydroxyapatite nanostructures (HAp NS). To generate HAp nanostructures with varied morphologies, the reaction was carried out across a range of time periods, such as 24 h at 80 C. The generated HAp NS was characterized using FTIR and FESEM. Additionally, it was demonstrated that the presence of BSA alters the shape of produced materials, which affects the reaction. FESEM revealed two distinct morphologies, including spherical and rod-like structures, both of which are very useful for a variety of biomedical applications.
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3. Fujishiro, Y., Hench, L.L. and Oonishi, H. (1997) ‘Quantitative rates of in vivo bone generation for Bioglass and hydroxyapatite particles as bone graft substitute’, Journal of materials science. Materials in medicine, 8(11), pp. 649–652.
4. Ganapathy, D. et al. (2022) ‘Rarity of mucormycosis in oral squamous cell carcinoma: A clinical paradox?’, Oral oncology, 125, p. 105725.
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6. Greish, Y.E. et al. (2005) ‘Composite formation from hydroxyapatite with sodium and potassium salts of polyphosphazene’, Journal of materials science. Materials in medicine, 16(7), pp. 613–620.
7. Guo B. et al. (2015) ‘[Inhibitory Effect of Hydroxyapatite Particles with Different Size on Malignant Melanoma A375 Cells: A Preliminary Study]’, Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 32(4), pp. 832–837.
8. Kanniah, P. et al. (2020) ‘Green synthesis of multifaceted silver nanoparticles using the flower extract of Aerva lanata and evaluation of its biological and environmental applications’, ChemistrySelect, 5(7), pp. 2322–2331.
9. Komlev, V.S., Barinov, S.M. and Koplik, E.V. (2002) ‘A method to fabricate porous spherical hydroxyapatite granules intended for time-controlled drug release’, Biomaterials, pp. 3449–3454. Available at: https://doi.org/10.1016/s0142-9612(02)00049-2.
10. Kumar, S.P. et al. (2020) ‘Targeting NM23-H1-mediated Inhibition of Tumour Metastasis in Viral Hepatitis with Bioactive Compounds from Ganoderma lucidum: A Computational Study’, Indian Journal of Pharmaceutical Sciences. Available at: https://doi.org/10.36468/pharmaceutical-sciences.650.
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16. Samuel, S.R., Mathew, M.G., et al. (2021) ‘Pediatric dental emergency management and
parental treatment preferences during COVID-19 pandemic as compared to 2019’, Saudi journal of biological sciences, 28(4), pp. 2591–2597.
17. Sobczak-Kupiec, A. et al. (2018) ‘Synthesis and characterization of ceramic - polymer composites containing bioactive synthetic hydroxyapatite for biomedical applications’, Ceramics International, pp. 13630–13638. Available at: https://doi.org/10.1016/j.ceramint.2018.04.199.
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21. Wong, C.-T. (no date) ‘Osteoconduction and osseointegration of a strontium-containing hydroxyapatite bioactive bone cement : in vitro and in vivo investigations’. Available at: https://doi.org/10.5353/th_b2994063.
22. Wu, C. et al. (2022) ‘Biomechanical and osteointegration study of 3D-printed porous PEEK hydroxyapatite-coated scaffolds’, Journal of biomaterials science. Polymer edition, pp. 1–14.
23. Yu, J. et al. (2014) ‘Synthesis, characterization, antimicrobial activity and mechanism of a novel hydroxyapatite whisker/nano zinc oxide biomaterial’, Biomedical materials , 10(1), p. 015001.
24. Zhang, B.-J. et al. (2017) ‘Enhanced osteogenesis of multilayered pore-closed microsphere-immobilized hydroxyapatite scaffold via sequential delivery of osteogenic growth peptide and BMP-2’, Journal of materials chemistry. B, Materials for biology and medicine, 5(41), pp. 8238–8253.
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Published
Jun 24, 2023
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How to Cite
George Franklin, Suganya Panneer Selvam, Satheesh Kumar Balu, Ramya Ramadoss, Sandhya Sundar, & Pratibha Ramani. (2023). Preparation Of Rod and Spherical Shaped Hydroxyapatite for Tissue Regeneration Application. Journal of Population Therapeutics and Clinical Pharmacology, 30(13), 408-413. https://doi.org/10.47750/jptcp.2023.30.13.042
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All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
George Franklin, Suganya Panneer Selvam, Satheesh Kumar Balu, Ramya Ramadoss, Sandhya Sundar, & Pratibha Ramani. (2023). Preparation Of Rod and Spherical Shaped Hydroxyapatite for Tissue Regeneration Application. Journal of Population Therapeutics and Clinical Pharmacology, 30(13), 408-413. https://doi.org/10.47750/jptcp.2023.30.13.042