Incidence of Postoperative Nausea and Vomiting in Patient Undergoing Sleeve Surgery with BMI > 35 Maintained with Isoflurane

Abstract

Background and aim: Patients with a body mass index (BMI) of 35 or above undergoing sleeve surgery under isoflurane anesthesia will be analyzed for their risk of experiencing postoperative nausea and vomiting (PONV). Isoflurane is a popular anesthetic used during sleeve surgery, and postoperative nausea and vomiting (PONV) is a typical consequence. The purpose of this study is to collect data on the frequency with which patients who have had sleeve gastrectomy experienced postoperative nausea and vomiting.
Material and method: In a prospective descriptive analysis, 55 patients who matched the inclusion criteria were randomly assigned to one of two groups using a non-randomized allocation approach. Blood pressure, end-tidal CO2, oxygen saturation, and heart rate were all measured and tracked for each patient. A consistent method of evaluating the frequency and severity of nausea and vomiting was used. Eligibility criteria included having a body mass index (BMI) over 35, being between the ages of 19 and 45, and having chosen to have gastric sleeve surgery as an elective procedure. Women with a body mass index (BMI) lower than 35 or pregnant were not eligible. The researchers determined that a sample size of n = 55 was appropriate. Convenience sampling was used to pick the participants. The research made that the sample was representative and that the sampling strategy could be implemented as planned.
Results: Age, sex, body mass index, length of operation, antiemetic medicine, smoking, nausea and vomiting history, and premedication are all factors that are analyzed. The study concludes that the two groups, those who experience and those who do not, differ significantly in terms of mean operation length, antiemetic drug use, and history of nausea and vomiting following surgery.There is no statistically significant difference in demographics such as age, gender, body mass index, smoking status, or premedication usage.
Conclusion: The objective of this study was to utilize logistic regression analysis to identify risk factors associated with postoperative nausea and vomiting (PONV). The findings revealed an inverse relationship between age and the incidence of PONV, while smoking was positively associated with PONV. The use of antiemetic medication, a higher body mass index (BMI), and longer surgical duration were also found to be correlated with an increased risk of PONV. However, there were no statistically significant correlations observed between preoperative treatment with Dexamethasone or ondansetron, gender, and the occurrence of PONV. Based on these results, the researchers concluded that these factors should be taken into consideration when assessing a patient's risk of experiencing postoperative nausea and vomiting during surgery.