Effect Of Bioactive Glass on Dentin Hypersensitivity – A Systematic Review
Main Article Content
Keywords
components, electronic, glass, bioactive
Abstract
Objective: To evaluate whether the dentifrice containing bioactive glass is more effective than dentifrice without bioactive glass in reduction of dentin hypersensitivity .
Is there any difference between the dentifrice containing bioactive glass and other dentifrice without bioactive glass in reduction of dentin hypersensitivity.
Sources: Five databases were searched to identify the relevant articles published up to December 2020 . Electronic databases were searched in PUBMED , Scopus ,LILACS , Cochrane Library and Google scholar . Two authors had performed the data extraction from the included studies . The primary outcome is to evaluate the response to thermal ,tactile ,cold stimulus for the treatment of dentine hypersensitivity and the secondary outcome is to compare the efficacy of desensitising agents used in the treatment of Dentine hypersensitivity. Each of the included studies was evaluated using the Cochrane Collaboration tool for assessing risk of bias .
Study Selection: Randomised controlled trials ( RCTs ) comparing desensitising toothpastes with a toothpaste without the desensitising components . This was evaluated in the patients who suffer from Dentin hypersensitivity were included . The risk of bias was assessed according to Cochrane guidelines using RevMan 5.3 software .
Data Collection: A total of 14 RCTs were included in this systematic review . It was clearly stated that the toothpastes that contain active desensitisation ingredients showed a better desensitising effect on Dentin hypersensitivity than that of other groups .
Conclusion: According to the 14 (RCT’s) included studies in this systematic review , the bioactive glass containing dentifrice had superior reduction of dentin hypersensitivity compared to dentifrice without bioactive glass .
References
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12. Li, Z. et al. (2020) ‘Apoptotic induction and anti-metastatic activity of eugenol encapsulated chitosan nanopolymer on rat glioma C6 cells via alleviating the MMP signaling pathway’, Journal of Photochemistry and Photobiology B: Biology, p. 111773. Available at: https://doi.org/10.1016/j.jphotobiol.2019.111773.
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15. Martins, C.C. et al. (2020) ‘Desensitizing Toothpastes for Dentin Hypersensitivity: A Network Meta-analysis’, Journal of dental research, 99(5), pp. 514–522.
16. Mohan, M. and Jagannathan, N. (2014) ‘Oral field cancerization: an update on current concepts’, Oncology reviews, 8(1), p. 244.
17. Neelakantan, P., Grotra, D. and Sharma, S. (2013) ‘Retreatability of 2 mineral trioxide aggregate-based root canal sealers: a cone-beam computed tomography analysis’, Journal of endodontia, 39(7), pp. 893–896.
18. Paramasivam, A. et al. (2020) ‘A novel COVID-19 and its effects on cardiovascular disease’, Hypertension research: official journal of the Japanese Society of Hypertension, pp. 729–730.
19. Salam T A, A. et al. (2023) ‘Assessment of Patients’ Experience and Perception Toward Dentinal Hypersensitivity for Its Diagnosis and Management: A Cross-Sectional Study’, Cureus, 15(2), p. e35214.
20. Sheriff, K.A.H., Ahmed Hilal Sheriff, K. and Santhanam, A. (2018) ‘Knowledge and Awareness towards Oral Biopsy among Students of Saveetha Dental College’, Research Journal of Pharmacy and Technology, p. 543. Available at: https://doi.org/10.5958/0974-360x.2018.00101.4.
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23. Ananthakrishna S, Raghu TN, Koshy S, Kumar N. Clinical evaluation of the efficacy of bioactive glass and strontium chloride for treatment of dentinal hypersensitivity. Journal of Interdisciplinary Dentistry. 2012 May 1;2(2):92.
24. Salian S, Thakur S, Kulkarni S, LaTorre G. A randomised controlled clinical study evaluating the efficacy of two desensitising dentifrices. Journal of Clinical Dentistry. 2010 Jan 1;21(3):82.
25. Seong J, Newcombe RG, Matheson JR, Weddell L, Edwards M, West NX. A randomised controlled trial investigating efficacy of a novel toothpaste containing calcium silicate and sodium phosphate in dentine hypersensitivity pain reduction compared to a fluoride control toothpaste. Journal of Dentistry. 2020 Jul 1;98:103320.
26. Rajesh KS, Hedge S, Kumar MA, Shetty DG. Evaluation of the efficacy of a 5% calcium sodium phosphosilicate (Novamin®) containing dentifrice for the relief of dentinal hypersensitivity: a clinical study. Indian Journal of Dental Research. 2012 May 1;23(3):363.
27. Milleman JL, Milleman KR, Clark CE, Mongiello KA, Simonton TC, Proskin HM. NUPRO sensodyne prophylaxis paste with NovaMin for the treatment of dentin hypersensitivity: a 4-week clinical study. American journal of dentistry. 2012 Oct 1;25(5):262.
28. C, Schmidlin PR, Michaelis M, Hirsch C, Attin T, Heumann C, Doméjean S, Gernhardt CR. Efficacy of 8% arginine on dentin hypersensitivity: a multicenter clinical trial in 273 patients over 24 weeks. Journal of dentistry. 2019 Apr 1;83:1-6.
29. Litkowski L, Greenspan DC. A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity—proof of principle. Journal of Clinical Dentistry. 2010 Jan 1;21(3):77.
30. Acharya AB, Surve SM, Thakur SL. A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity. Journal of clinical and experimental dentistry. 2013 Feb;5(1):e18.
31. Majji P, Murthy KR. Clinical efficacy of four interventions in the reduction of dentinal hypersensitivity: A 2-month study. Indian Journal of Dental Research. 2016 Sep 1;27(5):477.
32. Neuhaus KW, Milleman JL, Milleman KR, Mongiello KA, Simonton TC, Clark CE, Proskin HM, Seemann R. Effectiveness of a calcium sodium phosphosilicate containing prophylaxis paste in reducing dentine hypersensitivity immediately and 4 weeks after a single application: a double‐blind randomised controlled trial. Journal of clinical periodontology. 2013 Apr;40(4):349-57.
33. Sheng XY, Gong WY, Hu Q, Chen XF, Dong YM. Mineral formation on dentin induced by nano- bioactive glass. Chinese Chemical Letters. 2016 Sep 1;27(9):1509-14..
34. Comparative evaluation of demineralized bone matrix and type II collagen membrane versus eggshell powder as a graft material and membrane in rat modelAvinash Kavarthapu 1, Sankari Malaiappan 1DOI: 10.4103/ijdr.IJDR_489_17
35. Effects of dentifrices on discolouration of cad cam manufactured temporary restorative materials DOI:10.19070/2377-8075-21000927 36. Evaluation of remineralization potential and cytotoxicity of a novel strontium-doped nanohydroxyapatite paste: An in vitro studyRatheesh Rajendran 1, K Radhakrishnan Nair 2, Raghu Sandhya 1PMCID: PMC6635883 DOI: 10.1055/s-0039-1688735
37. Remineralization potential of dentifrice containing nanohydroxyapatite on artificial carious lesions of enamel: A comparative in vitro study PMID: 31543937
38. Improved quality of life in patients with dentin hypersensitivity.DOI: 10.1111/j.1365-2842.2008.01901.x
39. Bionic effects of nano hydroxyapatite dentifrice on demineralised surface of enamel post orthodontic debonding: in-vivo split mouth studyDOI: 10.1186/s40510-021-00381-5
2. Alaskar, N. (2016) Comparative Effectiveness Research of Dentin Hypersensitivity Intervention - A Mixed Systematic Review Analysis.
3. Aldhuwayhi, S. et al. (2021) ‘Covid-19 Knowledge and Perceptions Among Dental Specialists: A Cross-Sectional Online Questionnaire Survey’, Risk management and healthcare policy, 14, pp. 2851–2861.
4. Biria, M. et al. (2021) ‘In Vitro Effects of Three Fluoride-Free Pastes on Remineralization of Initial Enamel Carious Lesions’, Pediatric dentistry, 43(5), pp. 389–395.
5. Dua, K. et al. (2019) ‘The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress’, Drug development research, 80(6), pp. 714–730.
6. Earl, J.S. et al. (2011) ‘Physical and chemical characterization of dentin surface following treatment with NovaMin technology’, The Journal of clinical dentistry, 22(3), pp. 62–67.
7. Gan, H. et al. (2019) ‘Zingerone induced caspase-dependent apoptosis in MCF-7 cells and prevents 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in experimental rats’, Journal of biochemical and molecular toxicology, 33(10), p. e22387.
8. Gillam, D.G. (2015) Dentine Hypersensitivity: Advances in Diagnosis, Management, and Treatment. Springer.
9. Gillam, D. and Koyi, B. (2020) Dentin Hypersensitivity in Clinical Practice. JP Medical Ltd.
10. Jayaraj, G. et al. (2015) ‘Inter-observer agreement in grading oral epithelial dysplasia – A systematic review’, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, pp. 112–116. Available at: https://doi.org/10.1016/j.ajoms.2014.01.006.
11. Khijmatgar, S. et al. (2020) ‘Is there evidence for Novamin application in remineralization?: A Systematic review’, Journal of oral biology and craniofacial research, 10(2), pp. 87–92.
12. Li, Z. et al. (2020) ‘Apoptotic induction and anti-metastatic activity of eugenol encapsulated chitosan nanopolymer on rat glioma C6 cells via alleviating the MMP signaling pathway’, Journal of Photochemistry and Photobiology B: Biology, p. 111773. Available at: https://doi.org/10.1016/j.jphotobiol.2019.111773.
13. Maillard, M. et al. (2023) ‘The Effectiveness of Calcium Phosphates in the Treatment of Dentinal Hypersensitivity: A Systematic Review’, Bioengineering (Basel, Switzerland), 10(4). Available at: https://doi.org/10.3390/bioengineering10040447.
14. Markov, A. et al. (2021) ‘Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders’, Stem cell research & therapy, 12(1), p. 192.
15. Martins, C.C. et al. (2020) ‘Desensitizing Toothpastes for Dentin Hypersensitivity: A Network Meta-analysis’, Journal of dental research, 99(5), pp. 514–522.
16. Mohan, M. and Jagannathan, N. (2014) ‘Oral field cancerization: an update on current concepts’, Oncology reviews, 8(1), p. 244.
17. Neelakantan, P., Grotra, D. and Sharma, S. (2013) ‘Retreatability of 2 mineral trioxide aggregate-based root canal sealers: a cone-beam computed tomography analysis’, Journal of endodontia, 39(7), pp. 893–896.
18. Paramasivam, A. et al. (2020) ‘A novel COVID-19 and its effects on cardiovascular disease’, Hypertension research: official journal of the Japanese Society of Hypertension, pp. 729–730.
19. Salam T A, A. et al. (2023) ‘Assessment of Patients’ Experience and Perception Toward Dentinal Hypersensitivity for Its Diagnosis and Management: A Cross-Sectional Study’, Cureus, 15(2), p. e35214.
20. Sheriff, K.A.H., Ahmed Hilal Sheriff, K. and Santhanam, A. (2018) ‘Knowledge and Awareness towards Oral Biopsy among Students of Saveetha Dental College’, Research Journal of Pharmacy and Technology, p. 543. Available at: https://doi.org/10.5958/0974-360x.2018.00101.4.
21. Soares, P.V. and Grippo, J.O. (2017) Noncarious Cervical Lesions and Cervical Dentin Hypersensitivity: Etiology, Diagnosis, and Treatment. Quintessence Publishing (IL).
22. Sufi, F. et al. (2016) ‘Efficacy of an experimental toothpaste containing 5% calcium sodium phosphosilicate in the relief of dentin hypersensitivity: An 8-week randomized study (Study 1)’, American journal of dentistry, 29(2), pp. 93–100.
23. Ananthakrishna S, Raghu TN, Koshy S, Kumar N. Clinical evaluation of the efficacy of bioactive glass and strontium chloride for treatment of dentinal hypersensitivity. Journal of Interdisciplinary Dentistry. 2012 May 1;2(2):92.
24. Salian S, Thakur S, Kulkarni S, LaTorre G. A randomised controlled clinical study evaluating the efficacy of two desensitising dentifrices. Journal of Clinical Dentistry. 2010 Jan 1;21(3):82.
25. Seong J, Newcombe RG, Matheson JR, Weddell L, Edwards M, West NX. A randomised controlled trial investigating efficacy of a novel toothpaste containing calcium silicate and sodium phosphate in dentine hypersensitivity pain reduction compared to a fluoride control toothpaste. Journal of Dentistry. 2020 Jul 1;98:103320.
26. Rajesh KS, Hedge S, Kumar MA, Shetty DG. Evaluation of the efficacy of a 5% calcium sodium phosphosilicate (Novamin®) containing dentifrice for the relief of dentinal hypersensitivity: a clinical study. Indian Journal of Dental Research. 2012 May 1;23(3):363.
27. Milleman JL, Milleman KR, Clark CE, Mongiello KA, Simonton TC, Proskin HM. NUPRO sensodyne prophylaxis paste with NovaMin for the treatment of dentin hypersensitivity: a 4-week clinical study. American journal of dentistry. 2012 Oct 1;25(5):262.
28. C, Schmidlin PR, Michaelis M, Hirsch C, Attin T, Heumann C, Doméjean S, Gernhardt CR. Efficacy of 8% arginine on dentin hypersensitivity: a multicenter clinical trial in 273 patients over 24 weeks. Journal of dentistry. 2019 Apr 1;83:1-6.
29. Litkowski L, Greenspan DC. A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity—proof of principle. Journal of Clinical Dentistry. 2010 Jan 1;21(3):77.
30. Acharya AB, Surve SM, Thakur SL. A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity. Journal of clinical and experimental dentistry. 2013 Feb;5(1):e18.
31. Majji P, Murthy KR. Clinical efficacy of four interventions in the reduction of dentinal hypersensitivity: A 2-month study. Indian Journal of Dental Research. 2016 Sep 1;27(5):477.
32. Neuhaus KW, Milleman JL, Milleman KR, Mongiello KA, Simonton TC, Clark CE, Proskin HM, Seemann R. Effectiveness of a calcium sodium phosphosilicate containing prophylaxis paste in reducing dentine hypersensitivity immediately and 4 weeks after a single application: a double‐blind randomised controlled trial. Journal of clinical periodontology. 2013 Apr;40(4):349-57.
33. Sheng XY, Gong WY, Hu Q, Chen XF, Dong YM. Mineral formation on dentin induced by nano- bioactive glass. Chinese Chemical Letters. 2016 Sep 1;27(9):1509-14..
34. Comparative evaluation of demineralized bone matrix and type II collagen membrane versus eggshell powder as a graft material and membrane in rat modelAvinash Kavarthapu 1, Sankari Malaiappan 1DOI: 10.4103/ijdr.IJDR_489_17
35. Effects of dentifrices on discolouration of cad cam manufactured temporary restorative materials DOI:10.19070/2377-8075-21000927 36. Evaluation of remineralization potential and cytotoxicity of a novel strontium-doped nanohydroxyapatite paste: An in vitro studyRatheesh Rajendran 1, K Radhakrishnan Nair 2, Raghu Sandhya 1PMCID: PMC6635883 DOI: 10.1055/s-0039-1688735
37. Remineralization potential of dentifrice containing nanohydroxyapatite on artificial carious lesions of enamel: A comparative in vitro study PMID: 31543937
38. Improved quality of life in patients with dentin hypersensitivity.DOI: 10.1111/j.1365-2842.2008.01901.x
39. Bionic effects of nano hydroxyapatite dentifrice on demineralised surface of enamel post orthodontic debonding: in-vivo split mouth studyDOI: 10.1186/s40510-021-00381-5
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Published
Jun 6, 2023
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P.Niharika, & Iffat Nasim, M.D.S. (2023). Effect Of Bioactive Glass on Dentin Hypersensitivity – A Systematic Review. Journal of Population Therapeutics and Clinical Pharmacology, 30(14), 91-101. https://doi.org/10.47750/jptcp.2023.30.14.012
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How to Cite
P.Niharika, & Iffat Nasim, M.D.S. (2023). Effect Of Bioactive Glass on Dentin Hypersensitivity – A Systematic Review. Journal of Population Therapeutics and Clinical Pharmacology, 30(14), 91-101. https://doi.org/10.47750/jptcp.2023.30.14.012