A Deep Learning Model for Classification of Cancer Types on Gene Expression Data
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Keywords
Feature selection, Local Optimum, Dimensionality reduction, weight values and Fuzzy Logic
Abstract
Cancer Classification have great significance in cancer diagnostics and inventions of new drugs. Earlier researches in this area mostly focused on clinical aspects with low diagnostic capabilities. Classifying cancers using gene expression data have the ability to address most preliminary issues associated with diagnosis of cancers or inventions of drugs. Advancements in DNA micro-array approaches have opened the way to monitor thousands of gene expressions. This enterprising quality of gene expression data has been the impetus of this study which examines the feasibility of identifying cancers from gene expression data. For analysis of tumor types, this work proposed DFN Forest (Deep Flexible Neural Forest) model and introduced an improved model for cancer types classification. In this work, Principal Component Analysis (PCA) algorithm is used for dimensionality reduction. Feature selection is done with the help of ICA (Imperialist Competitive Algorithm). DFFN Forest (Deep Fuzzy Flexible Neural Forest), which uses fuzzy logic to update the weight values, is used in this work to classify cancer subtypes. Results from experiments show that the proposed model is effective in terms of metrics like precision, recall, accuracy, and error rate.
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