PRESCRIPTION PATTERN OF MEDICINES IN CHRONIC KIDNEY DISEASE PATIENTS IN NEPHROLOGY DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL: AN OBSERVATIONAL STUDY
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Keywords
Chronic Kidney Disease, Drug Utilization Pattern, Rationality, WHO Core Prescribing Indicators
Abstract
Objectives: Chronic Kidney Disease patients required lifelong multiple therapy. Multitudinous medication increases risk of irrational drug use and drugs related problems in CKD patients. This study was done to estimate the current trends of prescribing pattern of medicines in chronic kidney disease patients and to assess the rationality of prescriptions. Methods: A prospective observational study was conducted at a tertiary care teaching hospital. All the prescribing details of study participants including patient’s demographic details, diagnosis, drug name, dose, duration and frequency were recorded in specially designed performa and rationality of prescription was assessed using WHO core prescribing indicators. Results: Demographic analysis showed males predominance with 54% and females were 46%. Most of the study population belongs to the age group more than 40 years (50%). Anemia and Hypertension were the main co morbidities associated with CKD followed by diabetes. Most commonly prescribed drugs were cardiovascular drugs (18.24%) in which anti-hypertensive i.e. calcium channel blockers (24%) and diuretics (20%) were commonly used. Conclusions: The present study concluded that further improvements are needed in prescribing practices of CKD patients mainly in average number of drugs per prescription, prescription of drugs with generic names and prescription of drugs from the National essential medicines list.
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Sonika Niraj Motan
Dept. of Pharmacology, Mahatma Gandhi Medical College and Hospital, Jaipur 302022, (Rajasthan) India
Anusha Vohra
Mahatma Gandhi Medical College and Hospital, Jaipur
Mohammed Shoaib
Mahatma Gandhi Medical College and Hospital, Jaipur