Exploring the Knowledge of Oral Medicine Specialists towards Salivary Diagnostic Markers for Oral and Systemic Diseases
Main Article Content
Keywords
Attitude, Diagnostic markers, Knowledge, Oral Potentially Malignant Disorders, Precancerous conditions, Salivary markers
Abstract
Aim: To assess the knowledge, attitude and perception of salivary diagnostic markers among Oral Medicine Specialists.
Background: Early detection plays a crucial role in treatment planning and prognosis. Saliva serves as a potential diagnostic fluid as it is economic, non-invasive and gives information about oral & general health. Saliva can be used for clinical diagnosis, disease monitoring and decision making. Salivary constituent’s effective indicators of local and systemic disorders. Main problem is standardization of saliva collection methods as it is heterogeneous across studies.
Materials And Methods: A 15 multiple choice questionnaire was prepared by the principal investigator and the guide circulated among peers for validation. An online survey was created using google forms and distributed among Oral Medicine Specialists. Data was tabulated in Excel spreadsheets. Imported to IBM SPSS software version 2.0 and statistical analysis were performed. Frequency, percentage and chi square test was performed.
Results: Oral medicine specialists were mostly aware about recent salivary diagnostic markers. Majority of the participants believe that salivary biomarkers can serve as a diagnostic & prognostic tool. 70% of the participants feel that saliva can replace tissue or serum as a biomarker and can be translated into routine clinical practice.
Conclusion: Oral medicine specialists have adequate awareness and knowledge about salivary diagnostic markers, but certain knowledge has to be brushed up among them. Majority of participants showed a positive attitude towards its use as a diagnostic & prognostic tool. Furthermore, they need to be trained on these grounds to help them treat their patients in the best possible way.
References
2. Caillet J, Mignan S, Pham-Dang N, Devoize L. Analysis of leptin concentrations in oral fluids (saliva and crevicular gingival fluid) and blood in patients with chronic periodontal disease: systematic review of literature [Internet]. Vol. 26, Journal of Oral Medicine and Oral Surgery. 2020. p. 6. Available from: http://dx.doi.org/10.1051/mbcb/2019037
3. Meleti M, Cassi D, Vescovi P, Setti G, Pertinhez TA, Pezzi ME. Salivary biomarkers for diagnosis of systemic diseases and malignant tumors. A systematic review [Internet]. Medicina Oral Patología Oral y Cirugia Bucal. 2020. p. 0–0. Available from: http://dx.doi.org/10.4317/medoral.23355
4. Ogbureke KUE, Ogbureke EI. The History of Salivary Diagnostics. In: Streckfus CF, editor. Advances in Salivary Diagnostics. Berlin, Heidelberg: Springer Berlin Heidelberg; 2015. p. 17–31.
5. Naithani N, Bagaria A, Tihara P, Kumari S, Singh OK, Kaur G, et al. International Journal of Research in Health and Allied Sciences. ijrhas.com [Internet]. Available from: http://ijrhas.com/uploadfiles/29covidvol6issue3pp122-125.20200629062015.pdf
6. Yoshizawa JM, Schafer CA, Schafer JJ, Farrell JJ, Paster BJ, Wong DTW. Salivary biomarkers: toward future clinical and diagnostic utilities. Clin Microbiol Rev. 2013 Oct;26(4):781–91.
7. Proctor GB. The physiology of salivary secretion. Periodontol 2000. 2016 Feb;70(1):11–25.
8. Rathnayake N, Akerman S, Klinge B, Lundegren N, Jansson H, Tryselius Y, et al. Salivary biomarkers for detection of systemic diseases. PLoS One. 2013 Apr 24;8(4):e61356.
9. Malathi N, Mythili S, Vasanthi HR. Salivary diagnostics: a brief review. ISRN Dent. 2014 Jan 29;2014:158786.
10. Martins JR, Díaz-Fabregat B, Ramírez-Carmona W, Monteiro DR, Pessan JP, Antoniali C. Salivary biomarkers of oxidative stress in children with dental caries: Systematic review
and meta-analysis. Arch Oral Biol. 2022 Jul;139:105432.
11. Khandelwal A, Palanivelu A. Correlation Between Dental Caries And Salivary Albumin In Adult Population In Chennai: An In Vivo Study. BDS. 2019 Apr 30;22(2):228–33.
12. Maheswari TNU, Venugopal A, Sureshbabu NM, Ramani P. Salivary micro RNA as a potential biomarker in oral potentially malignant disorders: A systematic review. Ci Ji Yi Xue Za Zhi. 2018 Apr-Jun;30(2):55–60.
13. Uma Maheswari TN, Nivedhitha MS, Ramani P. Expression profile of salivary micro RNA-21 and 31 in oral potentially malignant disorders. Braz Oral Res. 2020 Feb 10;34:e002.
14. Sridharan G, Ramani P, Patankar S, Vijayaraghavan R. Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma. J Oral Pathol Med. 2019 Apr;48(4):299–306.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.