Comparative Evaluation of The Effectiveness of Different Surgical Techniques of Coronally Advanced Flap In Gingival Recession Management - A Systematic Review
Main Article Content
Keywords
complete root coverage; gingival recession; mucogingival surgery; root coverage; randomized controlled trial; minimally invasive flap; modified coronally advanced flap; coronally advanced flap; systematic review
Abstract
Background and objective : Although coronally advanced flap has been a gold standard technique for recession management, no systematic review has exclusively addressed the effectiveness of various surgical modifications of coronally advanced flap. A single technique addressing almost all the recession defects within a single visit, that is operator-friendly, time-efficient, no requirement for a second surgical site, and, most importantly, meeting the patient’s esthetic demands is always a preferable option. Coronally advanced flap (CAF) technique is the gold standard technique indicated for the management of Miller’s class I and class II gingival recession defects.
Aim: The aim of this systematic review was to appraise the effectiveness of different surgical modifications in coronally advanced flap techniques in the management of Gingival recessions.
Material and Methods : Randomized clinical trials with at least 3 months of follow-up comparing at least two techniques of coronally advanced flap for treatment of Miller Class I and II gingival recessions were identified. The primary outcome variable being the percentage of root coverage (%RC). The secondary outcomes were recession depth, recession width, clinical attachment gain, keratinized tissue gain, mean root coverage, complete root coverage, aesthetic satisfaction, tooth sensitivity, post-operative patient discomfort
Results: A total of 503 Millers class I and II gingival recessions in 264 subjects from 10 RCT’s included in this systematic review, which compared different techniques show that irrespective of the technique, there was a significant improvement in clinical outcome as compared to baseline. Comparison of the CAF with vertical releasing incisions and Tunnel technique, Coronally advanced flap showed better results. Whereas, CAF with and without vertical incisions had not shown significant difference except for the patient-related parameters favouring flap without vertical incision. Comparison of triangular CAF with trapezoidal CAF showed that triangular CAF had better results. Between CAF with tension and without tension, CAF without tension had favorable results. Long-term maintenance of the obtained recession coverage was not observed irrespective of the technique used except for one study.
Conclusion: CAF with vertical releasing incisions is better compared to CAF without vertical incisions when root coverage is the major outcome. Aesthetics and patient-related outcome parameters were significantly better for CAF without vertical releasing incisions. More clinical trials are needed to confirm these results as there was heterogeneity in the included studies and the number of studies comparing each technique were very few.
References
2. Çetiner D, Bodur A, Uraz A. Expanded Mesh Connective Tissue Graft for the Treatment of Multiple Gingival Recessions [Internet]. Vol. 75, Journal of Periodontology. 2004. p. 1167–72. Available from: http://dx.doi.org/10.1902/jop.2004.75.8.1167
3. Pini-Prato G, Franceschi D, Cairo F, Nieri M, Rotundo R. Classification of Dental Surface Defects in Areas of Gingival Recession [Internet]. Vol. 81, Journal of Periodontology. 2010. p. 885–90. Available from: http://dx.doi.org/10.1902/jop.2010.090631
4. Pini Prato GP, Baldi C, Nieri M, Franseschi D, Cortellini P, Clauser C, et al. Coronally advanced flap: the post-surgical position of the gingival margin is an important factor for achieving complete root coverage. J Periodontol. 2005 May;76(5):713–22.
5. Zucchelli G, De Sanctis M. Treatment of multiple recession-type defects in patients with esthetic demands. J Periodontol. 2000 Sep;71(9):1506–14.
6. Cairo F, Pini-Prato GP. A technique to identify and reconstruct the cementoenamel junction level using combined periodontal and restorative treatment of gingival recession. A prospective clinical study. Int J Periodontics Restorative Dent. 2010 Dec;30(6):573–81.
7. Ozcelik O, Haytac MC, Seydaoglu G. Treatment of multiple gingival recessions using a coronally advanced flap procedure combined with button application. J Clin Periodontol. 2011 Jun;38(6):572–80.
8. Zadeh HH. Minimally invasive treatment of maxillary anterior gingival recession defects by vestibular incision subperiosteal tunnel access and platelet-derived growth factor BB. Int J Periodontics Restorative Dent. 2011 Nov-Dec;31(6):653–60.
9. Zucchelli G, Mele M, Mazzotti C, Marzadori M, Montebugnoli L, De Sanctis M. Coronally advanced flap with and without vertical releasing incisions for the treatment of multiple gingival recessions: a comparative controlled randomized clinical trial. J Periodontol. 2009 Jul;80(7):1083–94.
10. Chao JC. A novel approach to root coverage: the pinhole surgical technique. Int J Periodontics Restorative Dent. 2012 Oct;32(5):521–31.
11. Allegri MA, Landi L, Zucchelli G. Non-carious cervical lesions associated with multiple gingival recessions in the maxillary arch. A restorative-periodontal effort for esthetic success. A 12-month case report. Eur J Esthet Dent. 2010 Spring;5(1):10–27.
12. Sridharan G, Ramani P, Patankar S, Vijayaraghavan R. Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma. J Oral Pathol Med. 2019 Apr;48(4):299–306.
13. Duraisamy R, Krishnan CS, Ramasubramanian H, Sampathkumar J, Mariappan S, Navarasampatti Sivaprakasam A. Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments. Implant Dent. 2019 Jun;28(3):289–95.
14. Vijayakumar Jain S, Muthusekhar MR, Baig MF, Senthilnathan P, Loganathan S, Abdul Wahab PU, et al. Evaluation of Three-Dimensional Changes in Pharyngeal Airway Following Isolated Lefort One Osteotomy for the Correction of Vertical Maxillary Excess: A Prospective Study. J Maxillofac Oral Surg. 2019 Mar;18(1):139–46.
15. Prabakar J, John J, Arumugham IM, Kumar RP, Sakthi DS. Comparing the Effectiveness of Probiotic, Green Tea, and Chlorhexidine- and Fluoride-containing Dentifrices on Oral Microbial Flora: A Double-blind, Randomized Clinical Trial. Contemp Clin Dent. 2018 Oct-Dec;9(4):560–9.
16. Kaarthikeyan G, Jayakumar ND, Sivakumar D. Comparative Evaluation of Bone Formation between PRF and Blood Clot Alone as the Sole Sinus-Filling Material in Maxillary Sinus Augmentation with the Implant as a Tent Pole: A Randomized Split-Mouth Study. J Long Term Eff Med Implants. 2019;29(2):105–11.
17. Ramesh A, Varghese S, Jayakumar ND, Malaiappan S. Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study. J Periodontol. 2018 Oct;89(10):1241–8.
18. Murthykumar K, Arjunkumar R, Jayaseelan VP. Association of vitamin D receptor gene polymorphism (rs10735810) and chronic periodontitis. J Investig Clin Dent. 2019 Nov;10(4):e12440.
19. Gajendran PL, Parthasarathy H, Tadepalli A. Comparative evaluation of cathepsin K levels in gingival crevicular fluid among smoking and nonsmoking patients with chronic periodontitis. Indian J Dent Res. 2018 Sep-Oct;29(5):588–93.
20. Lambris JD, Mastellos DC, Reis ES. Therapeutic Modulation of the Complement System: Clinical Indications and Emerging Drug Leads. Frontiers Media SA; 2020. 185 p.
21. Rajasekar A, Varghese SS. Bacterial Profile Associated with Peri-Implantitis: A Systematic Review. J Long Term Eff Med Implants. 2023;33(3):9–20.
22. Website [Internet]. Available from: doi: http://dx.doi.org/10.19070/2377-8075-21000779
23. Mony U, Priya Veeraraghavan V. “Rules” to the genetic progression of tumours deciphered: Is it time to think differently in treating oral cancer patients? Oral Oncol. 2022 Nov;134:106111.
24. Govindarasu M, Prathap L, Govindasamy R. Histone deacetylase inhibitors regulate the oral cancer via PI3K/AKT signaling pathway. Oral Oncol. 2022 Dec;135:106221.
25. Jabin Z, Jain G, Jaiswal M, Vishnu Priya V. Top 100 cited articles on Silver diamine fluoride-A bibliometric analysis. J Oral Biol Craniofac Res. 2022 May 18;12(4):413–20.
26. Devi SS, Dinesh S, Sivakumar A, Nivethigaa B, Alshehri A, Awadh W, et al. Reliability of Frankfort Horizontal Plane with True Horizontal Plane in Cephalometric Measurements. J Contemp Dent Pract. 2022 Sep 23;23(6):601–5.
27. Garapati B, Ramamurthy J, Shanmugam R. Formulation, development, and evaluation of anti-inflammatory and antimicrobial effects of a novel polyherbal mouthwash-An study. J Popul Ther Clin Pharmacol. 2022 Aug 15;29(3):e94–103.
28. Garapati B, Malaiappan S, Rajeshkumar S, Murthykumar K. Cytotoxicity of lycopene-mediated silver nanoparticles in the embryonic development of zebrafish-An animal study. J Biochem Mol Toxicol. 2022 Oct;36(10):e23173.
29. Pini-Prato G, Baldi C, Pagliaro U, Nieri M, Saletta D, Rotundo R, et al. Coronally advanced flap procedure for root coverage. Treatment of root surface: root planning versus polishing. J Periodontol. 1999 Sep;70(9):1064–76.
30. Romanos GE, Bernimoulin JP, Marggraf E. The double lateral bridging flap for coverage of denuded root surface: longitudinal study and clinical evaluation after 5 to 8 years. J Periodontol. 1993 Aug;64(8):683–8.
31. Marggraf E. A direct technique with a double lateral bridging flap for coverage of denuded root surface and gingiva extension. Clinical evaluation after 2 years. J Clin Periodontol. 1985 Jan;12(1):69–76.
32. Pini Prato G, Pagliaro U, Baldi C, Nieri M, Saletta D, Cairo F, et al. Coronally advanced flap procedure for root coverage. Flap with tension versus flap without tension: a randomized controlled clinical study. J Periodontol. 2000 Feb;71(2):188–201.
33. Zucchelli G, Stefanini M, Ganz S, Mazzotti C, Mounssif I, Marzadori M. Coronally Advanced Flap with Different Designs in the Treatment of Gingival Recession: A Comparative Controlled Randomized Clinical Trial. Int J Periodontics Restorative Dent. 2016 May;36(3):319–27.
34. Rajendran V, Uppoor A, Kadakampally D, Mannava Y. Comparison of minimally invasive coronally advanced flap and modified coronally advanced flap for the management of multiple adjacent gingival recession defects: A split mouth randomized control trial. J Esthet Restor Dent. 2018 Nov;30(6):509–15.
35. Ozenci I, Ipci SD, Cakar G, Yilmaz S. Tunnel technique versus coronally advanced flap with acellular dermal matrix graft in the treatment of multiple gingival recessions. J Clin Periodontol. 2015 Dec;42(12):1135–42.
36. Santamaria MP, Neves FL da S, Silveira CA, Mathias IF, Fernandes-Dias SB, Jardini MAN, et al. Connective tissue graft and tunnel or trapezoidal flap for the treatment of single maxillary gingival recessions: a randomized clinical trial. J Clin Periodontol. 2017 May;44(5):540–7.
37. Salhi L, Lecloux G, Seidel L, Rompen E, Lambert F. Coronally advanced flap versus the
pouch technique combined with a connective tissue graft to treat Miller’s class I gingival recession: a randomized controlled trial. J Clin Periodontol. 2014 Apr;41(4):387–95.
38. Tavelli L, Barootchi S, Di Gianfilippo R, Modarressi M, Cairo F, Rasperini G, et al. Acellular dermal matrix and coronally advanced flap or tunnel technique in the treatment of multiple adjacent gingival recessions. A 12-year follow-up from a randomized clinical trial. J Clin Periodontol. 2019 Sep;46(9):937–48.
39. Ahmedbeyli C, Dirikan Ipçi S, Cakar G, Yılmaz S, Chambrone L. Coronally advanced flap and envelope type of flap plus acellular dermal matrix graft for the treatment of thin phenotype multiple recession defects. A randomized clinical trial. J Clin Periodontol. 2019 Oct;46(10):1024–9.
40. Dayoub S, Hamadah O, Albonni H. Comparison of a Semilunar Coronally Positioned Flap and Conventional Coronally Advanced Flap for the Treatment of Gingival Recession: A Split-mouth, Randomized Prospective Comparative Controlled Clinical Trial [Internet]. Vol. 11, World Journal of Dentistry. 2020. p. 3–11. Available from: http://dx.doi.org/10.5005/jp-journals-10015-1697
41. Pini Prato GP, Franceschi D, Cortellini P, Chambrone L. Long-term evaluation (20 years) of the outcomes of subepithelial connective tissue graft plus coronally advanced flap in the treatment of maxillary single recession-type defects. J Periodontol. 2018 Nov;89(11):1290–9.