Effect Of Using Povidone Iodine and Herbal Propolis Antibacterial Mouth on Blood Pressure

Abstract

Oral bacteria have a key role in inorganic nitrate bioactivation as they catalyze the conversion of salivary nitrate to the more reactive nitrite anion. Recent studies have shown that blood pressure increases with prolonged use of antiseptic mouthwashes, and demonstrated that nitrates derived from endogenous NO-synthase are recycled to nitrites and NO, sufficient to modulate cardiovascular function.
Reduction of salivary nitrate by oral bacteria may contribute to preventing oral disease, as well as increasing systemic nitric oxide levels which may improve conditions such as hypertension and diabetes.
Nitric Oxide is a substance that has the task of relaxing blood vessels, while bacteria are tasked with the Nitrite Pathway process, so the elimination of these bacteria due to the use of mouthwash can affect blood pressure.
This study used 12 adult samples (n = 6 Povidone Iodine and n = 6 Herbal Propolis) with age criteria of 17-30 years, healthy body and no history of hypertension. effects on blood pressure from the use of Povidone Iodine and Herbal Propolis antibacterial mouthwash. The highest systolic increase occurred on day 3, with a Standard Deviation of PI = 5.05964 & HP = 3.76386. The sample experienced an increase in blood pressure of approximately <5 mmHg. These results indicate that Povidone Iodine and Herbal Propolis mouthwash have an effect on reducing the microbiome of oral bacteria, in this case nitrate reducing bacteria so that it can affect blood pressure.