A Evaluation Result of Treatment Plans Used In the Treat of Right Breast Tumors After Mastectomy
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Keywords
breast cancer, dosimetry characteristics, IMRT organs at risk, VMAT
Abstract
Breast cancer is the most frequent cancer among women. Surgery, chemotherapy and radiotherapy are the main aspects of breast cancer management. External beam radiotherapy has an effective role in local recurrence control. The goal of this research is to determine if the volumetric arc therapy (VMAT) technique achieved a greater advantage in terms of homogeneous dose distribution for the tumor in comparison with intensity modulated radiotherapy (IMRT) technique and also in terms of reducing the dose on organ at risk in treatment patients with right breast cancer. Patients with right-sided breast cancer who underwent modified radical mastectomy were eligible for the study. Dose volume histograms were used to examine the dose distribution for both the planning target volume and the organs at risk. VMAT plans increase dose for PTV where 95% of prescribed dose cover 95% (V95) of Chest wall (PTV C. W) when compared with IMRT plans (P-Value 0.00387). Mean dose of heart was significantly decreased in IMRT plans when compared with VMAT plans (P – Value 0.00988) . The dose distribution of VMAT plans was the same as or better than IMRT plans, and it was linked to a significant benefit in ipsilateral lung sparing (P – Value 0.00318). Based on our data, patients with right-sided breast cancer who are candidates for modified radical mastectomy may benefit more from VMAT. Our results revealed that VMAT should be the first choice for patients with right-sided breast cancer who are undergoing modified radical mastectomy.
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