Effects of N-acetylcysteine on Serum Creatinine Levels in Chronic Renal Impairment Patients
Main Article Content
Keywords
Chronic, Serum, Patients, Impairment
Abstract
Background information and goals: N-acetylcysteine (NAC), an amino acid, has been used for a long time as a protection against contrast-induced nephropathy (CIN). NAC's efficacy is questionable due to conflicting study results and signs that it can alter blood creatinine levels without influencing the glomerular filtration rate. However, the impact of N-acetylcysteine on blood creatinine following therapy with current NAC preventive dosages has not been examined in a population at risk for CIN.
References
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3. Shahin, Ahmed Y., et al. Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis. International Journal of Gynecology & Obstetrics 104.1 (2009): 44-48.
4. Amin, Ahmed F., Omar M. Shaaban, and Mohamed A. Bediawy. N-acetyl cysteine for treatment of recurrent unexplained pregnancy loss. Reproductive Biomedicine Online 17.5 (2008): 722-726.
5. Elgindy, Eman A., et al. N-acetyl cysteine: could it be an effective adjuvant therapy in ICSI cycles? A preliminary study. Reproductive biomedicine online 20.6 (2010): 789-796.
6. Allamaneni, Shyam SR. Oxidants and antioxidants in human fertility. Middle East Fertility Society Journal 9.3 (2004).
7. Wang, Qingjing, et al. Protective effects of Nacetylcysteine on acetic acid-induced colitis in a porcine model. BMC gastroenterology 13.1 (2013): 1-11.
8. Wierzbicki, Anthony S. Homocysteine and cardiovascular disease: a review of the evidence. Diabetes and Vascular Disease Research 4.2 (2007): 143-149.
9. Khosravi, Mehdi, Majid Shohrati, and Kiyanush Falaknazi. Does N-Acetyl Cysteine Have a Dose-Dependent Effect on Plasma Homocysteine Concentration in Patients Undergoing Hemodialysis?. Nephro-Urology Monthly 1.1 (2009): 27-32.
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11. Kurek, M., H. Barchańska, and M. Turek. Degradation processes of pesticides used in potato cultivations. Reviews of Environmental Contamination and Toxicology Volume 242 (2016): 105-151.
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13. Saoudi, Mongi, et al. Deltamethrin induced oxidative stress in kidney and brain of rats: Protective effect of Artemisia campestris essential oil. Biomedicine & Pharmacotherapy 94 (2017): 955-963.
14. Abdou, Rania H., and Mohamed M. Abdel-Daim. Alpha-lipoic acid improves acute deltamethrininduced toxicity in rats. Canadian journal of physiology and pharmacology 92.9 (2014): 773- 779.
15. Abdel-Daim, Mohamed M., Nevien KM Abdelkhalek, and Ahmed M. Hassan. Antagonistic activity of dietary allicin against deltamethrin-induced oxidative damage in freshwater Nile tilapia; Oreochromis niloticus. Ecotoxicology and environmental safety 111 (2015): 146-152.