Prevalence of gingival status of PCOS women visiting a dental college - an institution based study

Main Article Content

S.B. Sree lakshmi
Sankari malaiappan

Keywords

polycystic ovarian syndrome , gingival inflammation ,modified gingival index , reproductive women , body mass index, novel method, innovative method.

Abstract

Introduction : Almost 6.5–8% women of the reproductive age (18–45 years) suffer what is currently acknowledged as polycystic ovary disorder (PCOS), a perplexing sickness related with persistent an ovulation, hyperandrogenism, and various ovarian sores as trademark highlights .Wholesome changes because of a westernized diet and inactive way of life have brought about metabolic wellbeing unsettling influences affecting the metropolitan spaces of non-industrial countries like India and China, prompting a higher commonness of PCOS, roughly 9.13% to 36% in India and 2% to 7.5% in China.
Materials And Method: The study was conducted in a University setting. The subjects in the age group of 15- 45 years of age with PCOS were included in the present study. The sample size for the present study was 20 subjects with PCOS were selected from the outpatient visits to Saveetha Dental College & Hospital from November 2020 to February 2021. Subjects with systemic disease, subjects who were on medication for systemic diseases. The subjects were divided into two groups containing 20 subjects
Results: Figure 1 represents the association between modified gingival index for healthy and pcos women . The X-axis represents the modified gingival index and Y-axis represents the age group between 15-50 years . Blue colour represents healthy women and Green colour represents pcos women . With the mean score of modified gingival index 0.61were healthy women and 1.36 were pcos women . However this is statistically not significant with chi-square value - 21.42 and p-value = 0.3 (p-value > 0.05) hence insignificant.


Discussion: The present study was carried out on a total number of 40 women (20—healthy; 20—PCOS) with an age range of 15 to 45 years. The mean age in the PCOS group was 26.13 + 4.49 years, and in the healthy group 23.53 + 3.96 years. Most women belonged to a semi-urban locality with good female literacy levels. Hence, only BMI was assessed and socioeco- nomic considerations were not taken into account. The BMI was significantly higher for women in the PCOS group [23.83 ± 2.49] compared to healthy controls [22.50 ± 2.24].
Conclusion: Within the limitations of the present study, it can be con- cluded that relatively greater gingival inflammation was observed in patients with PCOS compared to healthy controls, independent of the risk factors present.

Abstract 63 | pdf Downloads 69

References

1. Porwal S, Tewari S, Sharma RK, Singhal SR, Narula SC. Periodontal status and high-sensitivity C-reactive protein levels in polycystic ovary
syndrome with and without medical treatment. J Periodontol. 2014 Oct;85(10):1380–9.
2. Qasemi M, Aleyasin A, Mahdian R, Ghanami Gashti N, Shabani Nashtaei M, Ashrafnezhad Z, et al. Cell-free mtDNA level and biomarker potency for ART outcome are different in follicular fluid of PCOS and non-PCOS women. Mitochondrion [Internet]. 2021 Apr 8; Available
from: http://dx.doi.org/10.1016/j.mito.2021.04.003
3. Popa S. The periodontal state of smoker versus non-smoker pregnant women – gingival inflammation on a significant lot of pregnant women in Romania [Internet]. Available from: http://dx.doi.org/10.26226/morressier.5ac383262afeeb00097a4190
4. Ionescu CA, Popescu I, Banacu M, Dimitriu M. Lifestyle Changes and Weight Loss: Effects in PCOS [Internet]. Debatable Topics in PCOS Patients. 2018. Available from: http://dx.doi.org/10.5772/intechopen.73298
5. PC034: The periodontal state of smoker versus non-smoker pregnant women - gingival inflammation on a significant lot of pregnant
women in Romania [Internet]. Vol. 45, Journal of Clinical Periodontology. 2018. p. 376–376. Available from: http://dx.doi.org/10.1111/jcpe.33_12916
6. Zhao Y. Excessive bodily retention of organochlorine pesticide is associated with energy imbalance and inflammation in women
with PCOS: a case control study [Internet]. Vol. 104, Fertility and Sterility. 2015. p. e131. Available from: http://dx.doi.org/10.1016/j.fertnstert.2015.07.403
7. Ando’ A, D’Alessandro AM. Erratum to: Chapter 4 in Psychological Implications of PCOS [Internet]. Metabolic Aspects of PCOS. 2015. p.
E1–E1. Available from: http://dx.doi.org/10.1007/978-3-319-16760-2_7
8. Moran L, Teede H, Vincent A. Vitamin D is independently associated with depression and inflammation in overweight women with and
without PCOS [Internet]. Vol. 4, Journal of Nutrition & Intermediary Metabolism. 2016. p. 37. Available from: http://dx.doi.org/10.1016/j.jnim.2015.12.290
9. Harris C, Cheung T. The PCOS Diet Book: How You Can Use the Nutritional Approach to Deal with Polycystic Ovary Syndrome. HarperThorsons; 2002. 368 p.
10. Szczuko M, Zapałowska-Chwyć M, Maciejewska D, Drozd A, Starczewski A, Stachowska E. Significant Improvement Selected Mediators of
Inflammation in Phenotypes of Women with PCOS after Reduction and Low GI Diet [Internet]. Vol. 2017, Mediators of Inflammation.
2017. p. 1–7. Available from: http://dx.doi.org/10.1155/2017/5489523
11. Pateguana NB, Fung J. The PCOS Plan: Prevent and Reverse Polycystic Ovary Syndrome through Diet and Fasting. Greystone Books Ltd; 2020. 224 p.
12. Aldhuwayhi, Sami, Sreekanth Kumar Mallineni, Srinivasulu Sakhamuri, Amar Ashok Thakare, Sahana Mallineni, Rishitha Sajja, Mallika Sethi, Venkatesh Nettam, and Azher Mohiuddin Mohammad. 2021. “Covid-19 Knowledge and Perceptions Among Dental Specialists: A CrossSectional Online Questionnaire Survey.” Risk Management and Healthcare Policy 14 (July): 2851–61.
13. Dua, Kamal, Ridhima Wadhwa, Gautam Singhvi, Vamshikrishna Rapalli, Shakti Dhar Shukla, Madhur D. Shastri, Gaurav Gupta, et al. 2019.
“The Potential of siRNA Based Drug Delivery in Respiratory Disorders: Recent Advances and Progress.” Drug Development Research 80 (6): 714–30.
14. Gan, Hongyun, Yaqing Zhang, Qingyun Zhou, Lierui Zheng, Xiaofeng Xie, Vishnu Priya Veeraraghavan, and Surapaneni Krishna Mohan.
2019. “Zingerone Induced Caspase-Dependent Apoptosis in MCF-7 Cells and Prevents 7,12-Dimethylbenz(a)anthracene-Induced Mammary
Carcinogenesis in Experimental Rats.” Journal of Biochemical and Molecular Toxicology 33 (10): e22387.
15. Jayaraj, Gifrina, Pratibha Ramani, Herald J. Sherlin, Priya Premkumar, and N. Anuja. 2015. “Inter-Observer Agreement in Grading Oral Epithelial Dysplasia – A Systematic Review.” Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. https://doi.org/10.1016/j.ajoms.2014.01.006.
16. Li, Zhenjiang, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Srinivasa Rao Bolla, Hariprasath Lakshmanan, Subramanian
Kumaran, Wilson Aruni, et al. 2020. “Apoptotic Induction and Anti-Metastatic Activity of Eugenol Encapsulated Chitosan Nanopolymer on
Rat Glioma C6 Cells via Alleviating the MMP Signaling Pathway.” Journal of Photochemistry and Photobiology B: Biology. https://doi.org/10.1016/j.jphotobiol.2019.111773
17. Markov, Alexander, Lakshmi Thangavelu, Surendar Aravindhan, Angelina Olegovna Zekiy, Mostafa Jarahian, Max Stanley Chartrand,
Yashwant Pathak, Faroogh Marofi, Somayeh Shamlou, and Ali Hassanzadeh. 2021. “Mesenchymal Stem/stromal Cells as a Valuable
Source for the Treatment of Immune-Mediated Disorders.” Stem Cell Research & Therapy 12 (1): 192.
18. Mohan, Meenakshi, and Nithya Jagannathan. 2014. “Oral Field Cancerization: An Update on Current Concepts.” Oncology Reviews 8 (1): 244.
19. Neelakantan, Prasanna, Deeksha Grotra, and Subash Sharma. 2013. “Retreatability of 2 Mineral Trioxide Aggregate-Based Root Canal
Sealers: A Cone-Beam Computed Tomography Analysis.” Journal of Endodontia 39 (7): 893–96.
20. Paramasivam, Arumugam, Jayaseelan Vijayashree Priyadharsini, Subramanian Raghunandhakumar, and Perumal Elumalai. 2020. “A Novel COVID19 and Its Effects on Cardiovascular Disease.” Hypertension Research: Official Journal of the Japanese Society of Hypertension.
21. Sheriff, K. Ahmed Hilal, K. Ahmed Hilal Sheriff, and Archana Santhanam. 2018. “Knowledge and Awareness towards Oral Biopsy among Students of Saveetha Dental College.” Research Journal of Pharmacy and Technology. https://doi.org/10.5958/0974-360x.2018.00101.4.
22. Malik A. Gingival inflammation and preterm birth: a case control study [Internet]. Available from: http://dx.doi.org/10.26226/morressier.5ac383232afeeb00097a4081
23. Johnstone E. Lean PCOS may be a genetically distinct from obese PCOS: lean women with polycystic ovary syndrome and their relatives
have no increased risk of T2DM [Internet]. Available from: http://dx.doi.org/10.26226/morressier.5af300b3738ab10027aa99cd
24. Pasquali R. Management of the metabolic syndrome and glucose intolerance in women with PCOS [Internet]. Novel Insights into the
Pathophysiology & Treatment of PCOS. 2013. p. 110–21. Available from: http://dx.doi.org/10.2217/ebo.12.271
25. Varadan M, Gopalkrishna P, Bhat PV, Kamath SU, S K, K TG, et al. Influence of polycystic ovary syndrome on the periodontal health of
Indian women visiting a secondary health care centre. Clin Oral Investig. 2019 Aug;23(8):3249–55.
26. Kovacs GT, Norman R. Polycystic Ovary Syndrome. Cambridge University Press; 2007.