Retinopathy of prematurity: prevalence and severity at maternity and children hospital in Najaf province ,Iraq
Main Article Content
Keywords
prevalence, infants, premature, retinopathy of prematurity
Abstract
Background: preterm infants are vulnerable to retinopathy of prematurity, which consider as a leading cause of blindness in premature neonates. Low birth weight and small gestational age had been identified as significant risk factors for the development and progression for this disease .
Aim of the study: To assess the prevalence and severity of retinopathy of prematurity among preterm infants at neonatal intensive care unit in Al zahraa maternity and children teaching hospital at Najaf convince ,Iraq.
Patients and methods: This is a prospective study which enrolled 134 preterm infants who had been referred to ROP unit at al zahraa maternity and children teaching hospital in the period from November 2019 till September 2021.
Results: In this study 134 preterm neonate were screened ,of them 45(33.6%) having retinopathy of prematurity and 99(66.4%) were not affected. There were 6 (13.3%) cases of ROP at stage 1 ,28 (62.2%) at stage 2 ,8 (17.2%) at stage 3 and 3 (6.7%) at stage 5. Plus disease was detected in 5 (3.7%) of cases.Type 2 ROP were found in two third of ROP cases (66.6 %) and one third of ROP cases were (33.3%) were classified as sever (type 1 ROP or stage 5). The mean birth weight and gestational age of the screened infants were 1532.3+_507.7(500 to 3000)grams, 30.4+_2.5(26 to 42) weeks respectively.67 (56.7%) of the neonate were males and 58 (43.3%) were females.
Conclusion: Retinopathy of prematurity is relatively common disorder affecting premature neonate of Najaf province in Iraq. The mean gestational age and birth weight were less in infants who had ROP when compared to those without ROP.
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2. Hameed B, Shyamanur K, Kotecha S, et al. Trends in the Incidence of Severe Retinopathy of Prematurity in a Geographically Defined
Population Over a 10-Year Period. PediatricsD. 2010 ;113(6): 1653.
3. Bashinsky AL. Retinopathy of prematurity. N C Med J. 2017;78(2):124–128. doi:10.18043/ncm.78.2.124
4. Terry TL. Extreme Prematurity and Fibroblastic Overgrowth of Persistent Vascular Sheath Behind Each Crystalline Lens*: I. Preliminary Report. American journal of ophthalmology. 1942 Feb 1;25(2):203-4.
5. 5-Xu Y, Zhou X, Zhang Q, Ji X, Zhang Q, Zhu J, Chen C, Zhao P. Screening for retinopathy of prematurity in China: a neonatal units–based
prospective study. Investigative ophthalmology & visual science. 2013 Dec 1;54(13):8229-36
6. AlBalawi HB, AlBalawi NS, AlSuhaimi NA, et al. Incidence and risk factors for retinopathy of prematurity in Tabuk City, KSA. Middle East Afr
J Ophthalmol. 2020;27(2):105–109. doi:10.4103/meajo.MEAJO_195_19
7. Chaves-Samaniego MJ, García Castejón M, Chaves-Samaniego MC, et al. Risk calculator for retinopathy of prematurity requiring treatment.
Front Pediatr. 2020;8:529639. doi:10.3389/fped.2020.529639 Hoyt CS.
8. Tylor D (2013) Retinopathy of Prematurity. In: Quinn G E, Fielder A R ,editors. Pediatric Ophthalmology and strabismus. Elsevier
Saunders 13: 432-448.
9. Smith LE. Through the eyes of a child: understanding retinopathy through ROP the Friedenwald lecture. Investigative ophthalmology & visual science. 2008 Dec 1;49(12):5177-82.
10. Chawla D, Agarwal R, Deorari AK, et al. Retinopathy of prematurity. The Indian Journal of Pediatrics. 2008; 75(1): 73-6.
11. International Committee for the Classification of Retinopathy of Prematurity. The international classification of retinopathy of prematurity
revisited. Archives of ophthalmology (Chicago, Ill.: 1960). 2005 Jul;123(7):991.
12. Zin AA, Magluta C, Pinto MF, Entringer AP, Mendes-Gomes MA, Moreira ME, Gilbert C. Retinopathy of prematurity screening and treatment cost in Brazil. Revista Panamericana de Salud Pública. 2014;36:37-43.
13. Gilbert C .retinopathy of prematurity.A global perspective of the epidemic,population of babies at risk and implications for control. Early hum Dev 2008,84:77-82
14. Uhumwangho O, Israel-Aina Y. Awareness and screening for retinopathy of prematurity among paediatricians in Nigeria. J West Afr Coll Surg. 2013;3(3):33–45.
15. Patwardhan SD, Azad R, Gogia V, Chandra P, Gupta S. Prevailing clinical practices regarding screening for retinopathy of prematurity among pediatricians in India: a pilot survey. Indian J Ophthalmol. 2011;59(6):427–430. doi:10.4103/0301-4738.86307
16. Vedantham V. Retinopathy of prematurity screening in the Indian population: It′ s time to set our own guidelines!. Indian journal of ophthalmology. 2007 Sep;55(5):329.
17. Fortes Filho JB, Barros CK, Costa MC, Procianoy RS. Results of a program for the prevention of blindness caused by retinopathy of prematurity in southern Brazil. Jornal de pediatria. 2007 Jun;83(3):209-16.
18. Bas AY, Koc E, Dilmen U, ROP Neonatal Study Group. Incidence and severity of retinopathy of prematurity in Turkey. British Journal of Ophthalmology. 2015 Oct 1;99(10):1311-4
19. Meraz-Gutiérrez MP, Olguín-Manríquez FJ, Arriola-López AE, Berrones-Medina D, Price KW, Morales-Canton V, Martínez-Castellanos
MA. Evidence to modify guidelines for routine retinopathy of prematurity screening to avoid childhood blindness in middle-income countries.
Revista Mexicana de Oftalmología. 2016 Jul 1;90(4):167-73.
20. Ekinci DY, Bayramoglu SE, Vural AD. The Incidence of Retinopathy of Prematurity in a Tertiary Care Center in Turkey.
21. Waheeb S, Alshehri K. Incidence of retinopathy of prematurity at two tertiary centers in Jeddah, Saudi Arabia. Saudi Journal of Ophthalmology. 2016 Apr 1;30(2):109-12.
22. Karkhaneh R, Mousavi SZ, Riazi-Esfahani M, Ebrahimzadeh SA, Roohipoor R, Kadivar M, Ghalichi L, Mohammadi SF, Mansouri MR.
Incidence and risk factors of retinopathy of prematurity in a tertiary eye hospital in Tehran. British Journal of Ophthalmology. 2008 Nov 1;92(11):1446-9.
23. Dogra MR, Narang S, Biswas C, Gupta A, Narang A. Threshold retinopathy of prematurity: ocular changes and sequelae following cryotherapy. Indian journal of ophthalmology. 2001 Apr 1;49(2):97.
24. Deshpande DA, Chaturvedi M, Gopal L, Ramachandran S, Shanmugasundaram R. Treatment of threshold retinopathy of
prematurity. Indian journal of ophthalmology. 1998 Mar 1;46(1):15.
25. ZADEH, Firoozeh Abolhasani, et al. Cytotoxicity evaluation of environmentally friendly synthesis Copper/Zinc bimetallic nanoparticles on MCF-7 cancer cells. Rendiconti Lincei. Scienze Fisiche e Naturali, 2022, 1-7 .
26. ROHMAH, Martina Kurnia, et al. Modulatory role of dietary curcumin and resveratrol on growth performance, serum immunity responses,
mucus enzymes activity, antioxidant capacity and serum and mucus biochemicals in the common carp, Cyprinus carpio exposed to abamectin. Fish & Shellfish Immunology, 2022, 129: 221-230 .
27. ARIF, Anam, et al. The functions and molecular mechanisms of Tribbles homolog 3 (TRIB3) implicated in the pathophysiology of cancer. International Immunopharmacology, 2023, 114: 109581 .
28. MARGIANA, Ria, et al. Functions and therapeutic interventions of non-coding RNAs associated with TLR signaling pathway in atherosclerosis. Cellular Signalling, 2022, 100: 110471
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30. MOHAMMED, Zainab; QASIM, Maytham T. The Relationship between Insulin Resistance and Hypertension in Patient with Hypertensive. HIV Nursing, 2022, 22.2: 1659–1663-1659–1663 .
31. Afarid M, Hosseini H, Abtahi B. Screening for retinopathy of prematurity in South of Iran. Middle East African journal of ophthalmology. 2012 Jul;19(3):277.
32. Reyes ZS, Al-Mulaabed SW, Bataclan F, Montemayor C, Ganesh A, Al-Zuhaibi S, AlWaili H, Al-Wahibi F. Retinopathy of prematurity: revisiting incidence and risk factors from Oman compared to other countries. Oman journal of ophthalmology. 2017 Jan;10(1):26
33. Roohipoor R, Karkhaneh R, Farahani A, Ebrahimiadib N, Modjtahedi B, Fotouhi A, Yaseri M, Khodabande A, Zarei M, Fuladi MI, Taheri A. Retinopathy of prematurity screening criteria in Iran: new screening guidelines. Archives of Disease in Childhood-Fetal and Neonatal Edition. 2016 Jul 1;101(4):F288-9
34. Rasoulinejad SA, Montazeri M. Retinopathy of prematurity in neonates and its risk factors: a seven year study in northern iran. The open ophthalmology journal. 2016;10:17.
35. Bassiouny RM, Ellakkany RS, Aboelkhair SA, Mohsen TA, Othman IS. Incidence and risk factors of retinopathy of prematurity in neonatal intensive care units: Mansoura, Egypt. Journal of the Egyptian Ophthalmological Society. 2017 Jul 1;110(3):71.
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Feb 11, 2023
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Farooq Mohamed Abbas, Hassanain Hassan Attar, & Mohammed Qassim Al nooyani. (2023). Retinopathy of prematurity: prevalence and severity at maternity and children hospital in Najaf province ,Iraq. Journal of Population Therapeutics and Clinical Pharmacology, 30(2), 91-100. https://doi.org/10.47750/jptcp.2023.1071
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All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Farooq Mohamed Abbas, Hassanain Hassan Attar, & Mohammed Qassim Al nooyani. (2023). Retinopathy of prematurity: prevalence and severity at maternity and children hospital in Najaf province ,Iraq. Journal of Population Therapeutics and Clinical Pharmacology, 30(2), 91-100. https://doi.org/10.47750/jptcp.2023.1071